Guidelines and considerations for the use of system suitability and quality control samples in mass spectrometry assays applied in untargeted clinical metabolomic …

D Broadhurst, R Goodacre, SN Reinke, J Kuligowski… - Metabolomics, 2018 - Springer
Background Quality assurance (QA) and quality control (QC) are two quality management
processes that are integral to the success of metabolomics including their application for the …

Quality assurance procedures for mass spectrometry untargeted metabolomics. a review

D Dudzik, C Barbas-Bernardos, A García… - … of pharmaceutical and …, 2018 - Elsevier
Untargeted metabolomics, as a global approach, has already proven its great potential and
capabilities for the investigation of health and disease, as well as the wide applicability for …

Metabolomics enables precision medicine:“a white paper, community perspective”

RD Beger, W Dunn, MA Schmidt, SS Gross, JA Kirwan… - Metabolomics, 2016 - Springer
Abstract Introduction: Background to metabolomics Metabolomics is the comprehensive
study of the metabolome, the repertoire of biochemicals (or small molecules) present in …

Nutrimetabolomics: an integrative action for metabolomic analyses in human nutritional studies

MM Ulaszewska, CH Weinert… - Molecular nutrition & …, 2019 - Wiley Online Library
The life sciences are currently being transformed by an unprecedented wave of
developments in molecular analysis, which include important advances in instrumental …

Untargeted LC/MS-based metabolic phenotyping (metabonomics/metabolomics): The state of the art

H Gika, C Virgiliou, G Theodoridis, RS Plumb… - … of Chromatography B, 2019 - Elsevier
Liquid chromatography (LC) hyphenated to mass spectrometry is currently the most widely
used means of determining metabolic phenotypes via both untargeted and targeted …

Exploring the human microbiome from multiple perspectives: factors altering its composition and function

D Rojo, C Méndez-García… - FEMS microbiology …, 2017 - academic.oup.com
Our microbiota presents peculiarities and characteristics that may be altered by multiple
factors. The degree and consequences of these alterations depend on the nature, strength …

Implementation of liquid chromatography–high resolution mass spectrometry methods for untargeted metabolomic analyses of biological samples: A tutorial

J Pezzatti, J Boccard, S Codesido, Y Gagnebin… - Analytica chimica …, 2020 - Elsevier
Untargeted metabolomics is now widely recognized as a useful tool for exploring metabolic
changes taking place in biological systems under different conditions. By its nature, this is a …

[HTML][HTML] The scientific challenges in moving from targeted to non-targeted mass spectrometric methods for food fraud analysis: A proposed validation workflow to bring …

D Cavanna, L Righetti, C Elliott, M Suman - Trends in Food Science & …, 2018 - Elsevier
Background Detecting and measuring food fraud is a challenging analytical task since a
very wide range of food ingredients and types may be adulterated by numerous potential …

From sample treatment to biomarker discovery: A tutorial for untargeted metabolomics based on GC-(EI)-Q-MS

A Mastrangelo, A Ferrarini, F Rey-Stolle, A Garcia… - Analytica chimica …, 2015 - Elsevier
This tutorial provides a comprehensive description of the GC-MS-based untargeted
metabolomics workflow including: ethical approval requirement, sample collection and …

Flow cytometry has a significant impact on the cellular metabolome

A Binek, D Rojo, J Godzien, FJ Rupérez… - Journal of proteome …, 2018 - ACS Publications
The characterization of specialized cell subpopulations in a heterogeneous tissue is
essential for understanding organ function in health and disease. A popular method of cell …