[HTML][HTML] Pathophysiology of fibrosis in the vocal fold: current research, future treatment strategies, and obstacles to restoring vocal fold pliability

Y Kumai - International journal of molecular sciences, 2019 - mdpi.com
Communication by voice depends on symmetrical vibrations within the vocal folds (VFs) and
is indispensable for various occupations. VF scarring is one of the main reasons for …

Adipose stem cells and skin repair

J Ho Jeong - Current stem cell research & therapy, 2010 - ingentaconnect.com
With the discovery of adipose stem cells (ASCs), 40 years after the identification of bone
marrow stem cells, a new era of active stem cell therapy has opened. The abundance of …

Intratunical injection of human adipose tissue–derived stem cells prevents fibrosis and is associated with improved erectile function in a rat model of Peyronie's …

F Castiglione, P Hedlund, F Van der Aa, TJ Bivalacqua… - European urology, 2013 - Elsevier
BACKGROUND: Peyronie's disease (PD) is a connective tissue disorder of the tunica
albuginea (TA). Currently, no gold standard has been developed for the treatment of the …

Effect of human adipose derived stem cells on scar formation and remodeling in a pig model: a pilot study

IS Yun, YR Jeon, WJ Lee, JW Lee, DK Rah… - Dermatologic …, 2012 - Wiley Online Library
Background Adipose‐derived stem cells (ASC s) have positive effects in the wound healing
process. Objective To clarify whether ASC s positively mitigate scar formation in the wound …

[HTML][HTML] Stem cell enriched lipotransfer reverses the effects of fibrosis in systemic sclerosis

A Almadori, M Griffin, CM Ryan, DF Hunt, E Hansen… - PLoS …, 2019 - journals.plos.org
Oro-facial fibrosis in systemic sclerosis (Scleroderma; SSc) has a major impact on mouth
function, facial appearance, and patient quality of life. Lipotransfer is a method of …

Adipose‐derived stem cell‐containing hyaluronic acid/alginate hydrogel improves vocal fold wound healing

YM Kim, SH Oh, JS Choi, S Lee, JC Ra… - The …, 2014 - Wiley Online Library
Objectives/Hypothesis The purpose of this study was to investigate the regenerative efficacy
of an injectable hyaluronic acid/mildly cross‐linked alginate hydrogel (HA/ALG hydrogel) …

Adipose-derived stem cells promote proliferation, migration, and tube formation of lymphatic endothelial cells in vitro by secreting lymphangiogenic factors

K Takeda, Y Sowa, K Nishino, K Itoh… - Annals of plastic …, 2015 - journals.lww.com
Adipose-derived stem cells (ADSCs) are a promising new therapeutic modality for several
diseases and have been applied to various clinical fields because of their multidifferentiation …

[HTML][HTML] Achievements and challenges in transplantation of mesenchymal stem cells in otorhinolaryngology

R Kaboodkhani, D Mehrabani… - Journal of Clinical …, 2021 - mdpi.com
Otorhinolaryngology enrolls head and neck surgery in various tissues such as ear, nose,
and throat (ENT) that govern different activities such as hearing, breathing, smelling …

[HTML][HTML] Cell therapy and vocal fold scarring

A Mattei, J Magalon, B Bertrand… - European annals of …, 2017 - Elsevier
Vocal fold microstructure is complex and can be affected by laryngeal microsurgery,
inducing scarring that prevents mechanical uncoupling of epithelium and muscle, leading to …

Feasibility of first injection of autologous adipose tissue–derived stromal vascular fraction in human scarred vocal folds: a nonrandomized controlled trial

A Mattei, B Bertrand, E Jouve, T Blaise… - … –Head & Neck …, 2020 - jamanetwork.com
Importance Patients with scarred vocal folds, whether congenitally or after phonosurgery,
often exhibit dysphonia that negatively affects daily life and is difficult to treat. The …