Receptor for the Advanced Glycation End Products (RAGE) Pathway in Adipose Tissue Metabolism

K Gutowska, K Czajkowski, A Kuryłowicz - International journal of …, 2023 - mdpi.com
Advanced glycation end products (AGEs) are mediators in the process of cellular
dysfunction in response to hyperglycemia. Numerous data indicate that the accumulation of …

Accelerated AGEing: The impact of advanced glycation end products on the prognosis of chronic kidney disease

E Dozio, L Caldiroli, P Molinari, G Castellano… - Antioxidants, 2023 - mdpi.com
Advanced glycation end products (AGEs) are aging products. In chronic kidney disease
(CKD), AGEs accumulate due to the increased production, reduced excretion, and the …

Circulating levels of AGEs and soluble RAGE isoforms are associated with all-cause mortality and development of cardiovascular complications in type 2 diabetes: a …

J Sabbatinelli, S Castiglione, F Macrì, A Giuliani… - Cardiovascular …, 2022 - Springer
Background Advanced glycation end-products (AGEs) and their interaction with the receptor
for advanced glycation end-products (RAGE) play a pivotal role in the development and …

Sarcopenia in chronic kidney disease: Focus on advanced glycation end products as mediators and markers of oxidative stress

E Dozio, S Vettoretti, G Lungarella, P Messa… - Biomedicines, 2021 - mdpi.com
Sarcopenia is common in chronic kidney disease (CKD), and it is independently associated
with morbidity and mortality. Advanced glycation end products (AGE) are mainly known as …

The role of soluble receptor for advanced glycation end-products (sRAGE) in the general population and patients with diabetes mellitus with a focus on renal function …

M Steenbeke, S De Bruyne, M De Buyzere… - Critical Reviews in …, 2021 - Taylor & Francis
Isoforms of the receptor for advanced glycation end-product (RAGE) protein, which lack the
transmembrane and the signaling (soluble RAGE or sRAGE) domains are hypothesized to …

Advanced glycation end products (Age) and soluble forms of age receptor: Emerging role as mortality risk factors in CKD

E Dozio, S Vettoretti, L Caldiroli, S Nerini-Molteni… - Biomedicines, 2020 - mdpi.com
Advanced glycation end-products (AGE) can promote chronic kidney disease (CKD)
progression and CKD-related morbidities. The soluble receptor for AGE (sRAGE) is a …

[HTML][HTML] Modulation of soluble receptor for advanced glycation end-products (RAGE) isoforms and their ligands in healthy aging

F Scavello, F Zeni, CC Tedesco, E Mensà… - Aging (Albany …, 2019 - ncbi.nlm.nih.gov
The receptor for advanced glycation end-products (RAGE) recognizes several ligands
involved in inflammatory diseases. Two circulating soluble isoforms exist: esRAGE derived …

Could AGE/RAGE-related oxidative homeostasis dysregulation enhance susceptibility to pathogenesis of cardio-metabolic complications in childhood obesity?

D Corica, T Aversa, RM Ruggeri, M Cristani… - Frontiers in …, 2019 - frontiersin.org
Background: Advanced glycation end-products (AGEs) and their cell receptor (RAGE) are
involved in the pathophysiology of cardio-metabolic diseases. Interaction of AGEs with …

Glycation and glycosylation in cardiovascular remodeling: focus on advanced glycation end products and O-linked glycosylations as glucose-related pathogenetic …

E Dozio, L Massaccesi… - Journal of clinical medicine, 2021 - mdpi.com
Glycation and glycosylation are non-enzymatic and enzymatic reactions, respectively, of
glucose, glucose metabolites, and other reducing sugars with different substrates, such as …

Soluble RAGE and skeletal muscle tissue RAGE expression profiles in lean and obese young adults across differential aerobic exercise intensities

ER Miranda, JT Mey, BK Blackburn… - Journal of Applied …, 2023 - journals.physiology.org
Nearly 40% of Americans have obesity and are at increased risk for developing type 2
diabetes. Skeletal muscle is responsible for> 80% of insulin-stimulated glucose uptake that …