Constructions and properties of physically cross-linked hydrogels based on natural polymers

J Yang, Y Chen, L Zhao, J Zhang, H Luo - Polymer Reviews, 2023 - Taylor & Francis
The diverse structures and unique properties of hydrogels have attracted significant
attentions in recent years. Compared to chemically cross-linked hydrogels, natural polymer …

Applications of chitosan-based biomaterials: From preparation to spinal cord injury neuroprosthetic treatment

W Xiang, H Cao, H Tao, L Jin, Y Luo, F Tao… - International Journal of …, 2023 - Elsevier
Spinal cord injury (SCI)-related disabilities are a serious problem in the modern society.
Further, the treatment of SCI is highly challenging and is urgently required in clinical …

[HTML][HTML] Functional hydrogels as therapeutic tools for spinal cord injury: New perspectives on immunopharmacological interventions

CM Walsh, JK Wychowaniec, DF Brougham… - Pharmacology & …, 2022 - Elsevier
Spinal cord injury (SCI) is a complex medical and psychological challenge for which there is
no curative therapy currently available. Despite major progress in pharmacological and …

[HTML][HTML] Spatiotemporal dynamics of the cellular components involved in glial scar formation following spinal cord injury

C Zhang, J Kang, X Zhang, Y Zhang, N Huang… - Biomedicine & …, 2022 - Elsevier
Spinal cord injury (SCI) triggers complex inflammatory and pathological processes that
ultimately lead to scar formation, thus resulting in the severe and irreversible loss of function …

Multimodal therapy strategies based on hydrogels for the repair of spinal cord injury

Y Wang, HQ Lv, X Chao, WX Xu, Y Liu, GX Ling… - Military Medical …, 2022 - Springer
Spinal cord injury (SCI) is a serious traumatic disease of the central nervous system, which
can give rise to the loss of motor and sensory function. Due to its complex pathological …

[HTML][HTML] Hydrogels as delivery systems for spinal cord injury regeneration

D Silva, RA Sousa, AJ Salgado - Materials Today Bio, 2021 - Elsevier
Spinal cord injury is extremely debilitating, both at physiological and psychological levels,
changing completely the patient's lifestyle. The introduction of biomaterials has opened a …

Application of injectable hydrogels as delivery Systems in Spinal Cord Injury

R Ji, Z Hao, H Wang, X Li, L Duan, F Guan, S Ma - Gels, 2023 - mdpi.com
Spinal cord injury (SCI) is a severe neurological injury caused by traffic accidents, trauma, or
falls, which leads to significant loss of sensory, motor, and autonomous functions and …

Biomaterial-mediated factor delivery for spinal cord injury treatment

F Pinelli, F Pizzetti, V Veneruso, E Petillo, M Raghunath… - Biomedicines, 2022 - mdpi.com
Spinal cord injury (SCI) is an injurious process that begins with immediate physical damage
to the spinal cord and associated tissues during an acute traumatic event. However, the …

Fibrinolytic serine proteases, therapeutic serpins and inflammation: fire dancers and firestorms

JR Yaron, L Zhang, Q Guo, SE Haydel… - Frontiers in …, 2021 - frontiersin.org
The making and breaking of clots orchestrated by the thrombotic and thrombolytic serine
protease cascades are critical determinants of morbidity and mortality during infection and …

Modulating neuroinflammation through molecular, cellular and biomaterial‐based approaches to treat spinal cord injury

CYP Lee, WH Chooi, SY Ng… - … & Translational Medicine, 2023 - Wiley Online Library
The neuroinflammatory response that is elicited after spinal cord injury contributes to both
tissue damage and reparative processes. The complex and dynamic cellular and molecular …