The individualization of chromosomes during early mitosis and their clustering upon exit
from cell division are two key transitions that ensure efficient segregation of eukaryotic …

Over the past few decades, unbiased approaches such as genetic screening and protein
affinity purification have unveiled numerous proteins involved in DNA double-strand break …

During mitosis, condensin activity is thought to interfere with interphase chromatin structures.
To investigate genome folding principles in the absence of chromatin loop extrusion, we …

Emerging evidence underscores the critical role of impaired mRNA translation in various
neurobiological conditions. Ribosomal RNA (rRNA), essential for protein synthesis …

U3 snoRNA is essential for ribosome biogenesis during interphase. Upon mitotic onset, the
nucleolus disassembles and U3 snoRNA relocates to the perichromosomal region (PR) to …

The exonuclease ISG20L2 has been initially characterized for its role in the mammalian 5.8
S rRNA 3′ end maturation, specifically in the cleavage of ITS2 of 12S precursor ribosomal …

During mitosis, condensin activity interferes with interphase chromatin structures. Here, we
generated condensin-free mitotic chromosomes to investigate genome folding principles. Co …

The faithful transmission of a cell's identity and functionality to its daughters during mitosis
requires the proper assembly of mitotic chromosomes from interphase chromatin in a …

Nuclear lipids play roles in regulatory processes such as signaling, transcriptional
regulation, and DNA repair. In this report, we demonstrate that nuclear lipids may contribute …

Ustilaginoidea virens causes rice false smut, one of the most devastating rice diseases. The
pathogen produces various types of mycotoxins, such as ustilaginoidins and ustiloxins …