It is increasingly recognized that certain fundamental changes in diet and lifestyle that
occurred after the Neolithic Revolution, and especially after the Industrial Revolution and the …

Human life histories are shaped by the allocation of metabolic energy to competing
physiological domains. A model framework of the pathways of energy allocation is described …

A novel hypothesis of obesity is suggested by consideration of diet-related inflammation and
evolutionary medicine. The obese homeostatically guard their elevated weight. In rodent …

Intervertebral disc degeneration (IVDD), for which obesity and genetics are known risk
factors, is a chronic process that alters the structure and function of the intervertebral discs …

In social relationshipsÑwhether between mates, parents and offspring, or friendsÑwe find
much of lifeÕs meaning. But in these relationships, so critical to our well-being, might we …

Background Obesity has become the main health issue in developed countries as it impacts
life expectancy and increases mortality of cerebrovascular or cardiovascular diseases. The …

Background Recently, we reported signs of inflammation (raised IL-8, reduced miR-146a)
and signs of vascular repair (raised HGF) in the serum of Ecuadorian patients with type 2 …

To determine the population variation in the androgen receptor (AR) and its association with
body composition in a subsistence population, we sampled 87 settled and 65 nomadic …

Objectives: This study examined the association between the serum leptin level and body
mass index (BMI) and the effects of urbanization and polymorphisms of leptin (LEP) or leptin …

Living organisms are flexible; they can respond to changing conditions through a variety of
morphological, physiological, and behavioral mechanisms. The processes that organisms …