Since ancient times, Cannabis and its preparations have found various applications such as
for medical, recreational and industrial purposes. Subsequently the 1930s, legislation in …

The enduring relationship between humanity and the cannabis plant has witnessed
significant transformations, particularly with the widespread legalization of medical …

For millennia, Cannabis sativa has served diverse roles, from medicinal applications to
recreational use. Despite its extensive historical use, only a fraction of its components have …

Oxidative stress, characterized by increased production of reactive oxygen species (ROS)
and disturbed redox homeostasis, is one of the key mechanisms underlying synaptic loss …

The underlying pathogenesis of chronic inflammatory pain is greatly complex, but the
relevant therapies are still unavailable. Development of effective candidates for chronic …

Early adversity, the loss of the inhibitory GABAergic interneuron parvalbumin, and elevated
neuroinflammation are associated with depression. Individuals with a maltreatment history …

Background/Objectives: Cisplatin, a common chemotherapy agent, is well known to cause
severe side effects in the gastrointestinal and nervous systems due to its toxic and pro …

Unfortunately, the software that the authors used, Comprehensive Meta-Analysis Software,
rather confusingly reports a “Q* statistic”(along with an I2 value calculated from this value of …

Cannabinoid receptors, endogenous cannabinoids (endocannabinoids), and the enzymes
involved in the biosynthesis and degradation of the endocannabinoids make up the …

INTRODUCTION: The kinetics of ligand binding to G protein-coupled receptors (GPCRs) is
an important determining factor in the preclinical evaluation of a molecule. Therefore, efforts …