Structures of the common cyclodextrins and their larger analogues beyond the doughnut

W Saenger, J Jacob, K Gessler, T Steiner… - Chemical …, 1998 - ACS Publications
If the amylose fraction of starch is degraded by glucosyltransferases, one or several turns of
the amylose helix are hydrolyzed off and their ends are joined together, thereby producing …

NMR studies of chiral recognition by cyclodextrins

H Dodziuk, W Koźmiński… - … , Biological, and Chemical …, 2004 - Wiley Online Library
Chiral recognition by cyclodextrins is of considerable importance, especially for
pharmaceutical industry, in view of the possible side effects of the second enantiometer of …

Thermal analysis of cyclodextrins and their inclusion compounds

F Giordano, C Novak, JR Moyano - Thermochimica Acta, 2001 - Elsevier
This review examines the literature concerning the thermal properties of natural and
semisynthetic cyclodextrins and their inclusion compounds. Particular emphasis is given to …

Active-site gorge and buried water molecules in crystal structures of acetylcholinesterase from Torpedo californica

G Koellner, G Kryger, CB Millard, I Silman… - Journal of Molecular …, 2000 - Elsevier
Buried water molecules and the water molecules in the active-site gorge are analyzed for
five crystal structures of acetylcholinesterase from Torpedo californica in the resolution …

Molecules with holes–cyclodextrins

H Dodziuk - Cyclodextrins and their complexes: chemistry …, 2006 - Wiley Online Library
Cyclodextrins, CyDs, are macrocyclic oligosugars most commonly composed of 6, 7, or 8
glucosidic units bearing the names a-1, b-2 and g-3 CyD, respectively [1–3]. Other, usually …

Rigidity versus flexibility. A review of experimental and theoretical studies pertaining to the cyclodextrin nonrigidity

H Dodziuk - Journal of Molecular Structure, 2002 - Elsevier
For many years on the basis of X-ray studies cyclodextrins were considered to have a rigid
truncated-cone structure although this concept was incompatible with the ease of their …

Probing pseudopolymorphic transitions in pharmaceutical solids using Raman spectroscopy: Hydration and dehydration of theophylline

AM Amado, MM Nolasco, PJA Ribeiro-Claro - Journal of pharmaceutical …, 2007 - Elsevier
Theophylline is known to undergo vapor phase induced hydrate–anhydrate
pseudopolymorphic transformations, which can affect its bioavailability. In this work, the …

A molecular dynamics study of conformations of beta-cyclodextrin and its eight derivatives in four different solvents

W Khuntawee, M Karttunen… - Physical Chemistry …, 2017 - pubs.rsc.org
Understanding the atomic level interactions and the resulting structural characteristics is
required for developing beta-cyclodextrin (βCD) derivatives for pharmaceutical and other …

Role of cellulose ether polymers on ibuprofen release from matrix tablets

ML Vueba, LAE Batista de Carvalho… - Drug development …, 2005 - Taylor & Francis
Cellulose derivatives are the most frequently used polymers in formulations of
pharmaceutical products for controlled drug delivery. The main aim of the present work was …

A volumetric study of β-cyclodextrin/hydrocarbon and β-cyclodextrin/fluorocarbon surfactant inclusion complexes in aqueous solutions

LD Wilson, RE Verrall - The Journal of Physical Chemistry B, 1997 - ACS Publications
The apparent molar volumes (V ϕ, S) of a homologous series of hydrocarbon (hc)(C x H2 x+
1CO2Na, x= 2, 5− 9, 11, 13) and perfluorocarbon (fc)(C x F2 x+ 1CO2Na, x= 1, 3, 4, 6− 9) …