A decade ago, just five drugs were licensed for the treatment of viral infections. Since then,
greater understanding of viral life cycles, prompted in particular by the need to combat …

This systematic review addresses 2 questions pertinent to the need for pretreatment liver
biopsy in patients with chronic hepatitis C: how well do liver biopsy results predict treatment …

In chronic viral hepatitis, liver biopsy is performed to grade and stage liver damage. Liver
biopsy samples are usually taken with a needle using a percutaneous procedure. This …

Objectives: To assess the clinical-effectiveness and cost-effectiveness of pegylated
interferon-α combined with ribavirin in the treatment of chronic hepatitis C. Data sources …

This systematic review addressed 3 issues regarding current treatments for chronic hepatitis
C:(1) efficacy and safety in treatment-naive patients;(2) efficacy and safety in selected …

BACKGROUND Patients with chronic hepatitis C are at risk of developing type 2 diabetes
mellitus (DM) and impaired fasting glucose (IFG), and this risk may increase among hepatitis …

Abstract Relatively few patients (≤ 20%) with chronic hepatitis C achieve a sustained
virological response after interferon-α monotherapy. Hence, alternative treatment strategies …

Objectives: Lactoferrin has been reported to inhibit hepatitis C virus (HCV) infection in
cultured human hepatocytes and HCV viremia in patients with chronic hepatitis C (CHC) …

Interferon and ribavirin decrease necroinflammation in chronic hepatitis C with or without
virological clearance; however, reversibility of fibrosis remains to be established. We …

Background: Hepatitis C virus is a small, enveloped single stranded, positive sense RNA
virus. Different genotypes are distributed in different geographical areas of the world …