Abstract Hypoxia‑ischemia (H‑I) is frequently observed in perinatal asphyxia and other
diseases. It can lead to serious cardiac injury, cerebral damage, neurological disability and …

Hypoxic–ischemic encephalopathy, also referred as HIE, is a type of brain injury or damage
that is caused by a lack of oxygen to the brain during neonatal period. The incidence is …

Abstract l-Carnitine functions to transport long chain fatty acyl-CoAs into the mitochondria for
degradation by β-oxidation. Treatment with l-carnitine can ameliorate metabolic imbalances …

Importance The ability to predict neurodevelopmental impairment (NDI) for infants
diagnosed with hypoxic ischemic encephalopathy (HIE) is important for parental guidance …

Background Newborn animal studies and pilot studies in humans suggest that mild
hypothermia following peripartum hypoxia‐ischaemia in newborn infants may reduce …

Perinatal hypoxia-ischemia remains the primary cause of acute neonatal brain injury,
leading to a high mortality rate and long-term neurological deficits, such as behavioral …

Data from large randomized clinical trials indicate that therapeutic hypothermia, using either
selective head cooling or systemic cooling, is an effective therapy for neonatal …

Objective To evaluate serum neuronal and inflammatory biomarkers to determine whether
measurements of umbilical cords at birth can stratify severity of hypoxic-ischemic …

Objectives To evaluate plasma brain specific proteins and cytokines as biomarkers of brain
injury in newborns with hypoxic-ischemic encephalopathy (HIE) and, secondarily, to assess …

OBJECTIVE: To determine the safety and pharmacokinetics of erythropoietin (Epo) given in
conjunction with hypothermia for hypoxic-ischemic encephalopathy (HIE). We hypothesized …