Exosomes are a type of extracellular vesicles, produced within multivesicular bodies, that
are then released into the extracellular space through a merging of the multivesicular body …

Extracellular vesicles (EVs) are a heterogeneous group of natural particles that are relevant
to the treatment of cardiovascular diseases. These endogenous vesicles have certain …

Owing to the relationship between extracellular vesicles (EVs) and physiological and
pathological conditions, the interest in EVs is exponentially growing. EVs hold high hopes …

Exosomes are small membrane-bound vesicles of endocytic origin that are actively
secreted. The potential of exosomes as effective communicators of biological signaling in …

Exosomes can deliver therapeutic RNAs to neurons. The composition and the safety profile
of exosomes depends on the type of the exosome-producing cell. Mesenchymal stem cells …

Currently, brain natriuretic peptide (BNP) and N-terminal proBNP (NT-proBNP) are widely
used as diagnostic biomarkers for heart failure (HF) and cardiac dysfunction in clinical …

Drug-eluting stents implanted after ischaemic injury reduce the proliferation of endothelial
cells and vascular smooth muscle cells and thus neointimal hyperplasia. However, the …

Extracellular vesicles (EVs)—particularly exosomes and microvesicles (MVs)—are attracting
considerable interest in the cardiovascular field as the wide range of their functions is …

Poor reproducibility within and across studies arising from lack of knowledge regarding the
performance of extracellular RNA (exRNA) isolation methods has hindered progress in the …

Rationale: Paracrine secretions seem to mediate therapeutic effects of human CD34+ stem
cells locally transplanted in patients with myocardial and critical limb ischemia and in animal …