Background MicroRNAs (miRNAs) are small RNA molecules that regulate the expression of
corresponding messenger RNAs (mRNAs). Variations in the level of expression of distinct …

Breast cancer is a complex and heterogeneous disease. Signaling by estrogen receptor
(ER), progesterone receptor (PR), and/or human EGF-like receptor 2 (HER2) is a main driver …

Introduction Breast cancer (BC) is the most frequent malignant disease in women worldwide
and is therefore challenging for the healthcare system. Early BC detection remains a leading …

Background MiRNA expression profiling is being actively investigated as a clinical
biomarker and diagnostic tool to detect multiple cancer types and stages as well as other …

BACKGROUND: Many microRNAs (miRNAs) exhibit altered expression levels in cancers,
and they may be considered as valuable prognostic biomarkers for cancers. Here we aimed …

Background MicroRNAs (miRNAs) are a novel class of endogenous, non-coding, single-
stranded RNAs capable of regulating gene expression by suppressing translation or …

MicroRNAs (miRNAs) participate in diverse biological pathways and may act as oncogenes
or tumor suppressors. Single nucleotide polymorphisms (SNPs) in miRNAs (MirSNPs) might …

Breast cancer (BC), a heterogeneous, aggressive illness with high mortality, is essentially a
genomic disease. While the high-penetrance genes BRCA1 and BRCA2 play important …

Common genetic variants (single nucleotide polymorphisms SNPs) in microRNA (miRNA)
genes may alter their maturation or expression and play a role in the formation of human …

Esophageal cancer is the eighth most common cancer and sixth leading cause of cancer
associated death worldwide. Besides environmental risk factors, genetic factors might play …