Treatment of posttraumatic stress disorder: a state-of-the-art review

L Burback, S Brult-Phillips, MJ Nijdam… - Current …, 2024 - benthamdirect.com
This narrative state-of-the-art review paper describes the progress in the understanding and
treatment of Posttraumatic Stress Disorder (PTSD). Over the last four decades, the scientific …

A neurobiological framework for the therapeutic potential of music and sound interventions for post-traumatic stress symptoms in critical illness survivors

U Pant, M Frishkopf, T Park, CM Norris… - International Journal of …, 2022 - mdpi.com
Overview: Post traumatic stress disorder (PTSD) has emerged as a severely debilitating
psychiatric disorder associated with critical illness. Little progress has been made in the …

Epigenetics of traumatic stress: The association of NR3C1 methylation and posttraumatic stress disorder symptom changes in response to narrative exposure therapy

S Wilker, V Vukojevic, A Schneider, A Pfeiffer… - Translational …, 2023 - nature.com
Epigenetic processes allow plasticity in gene regulation in response to significant
environmental events. Accumulating evidence suggests that effective psychotherapy is …

Glucocorticoid-based pharmacotherapies preventing PTSD

A Florido, ER Velasco, S Monari, M Cano… - …, 2023 - Elsevier
Posttraumatic stress disorder (PTSD) is a highly disabling psychiatric condition that may
arise after exposure to acute and severe trauma. It is a highly prevalent mental disorder …

Genes and hormones of the hypothalamic–pituitary–adrenal axis in post-traumatic stress disorder. What is their role in symptom expression and treatment response?

S Fischer, T Schumacher, C Knaevelsrud… - Journal of Neural …, 2021 - Springer
Background Less than half of all individuals with post-traumatic stress disorder (PTSD) remit
spontaneously and a large proportion of those seeking treatment do not respond sufficiently …

Gene-environment interaction between HPA-axis genes and trauma exposure in the suicide behavior: A systematic review

TB González-Castro, IE Juárez-Rojop… - Journal of psychiatric …, 2023 - Elsevier
Suicide behavior (SB) emerge from complex interactions among traumatic events and
multiple genetic factors. We conducted the first systematic review to assess the evidence of a …

On making (and turning adaptive to) maladaptive aversive memories in laboratory rodents

L Gazarini, CAJ Stern, LJ Bertoglio - Neuroscience & Biobehavioral …, 2023 - Elsevier
Fear conditioning and avoidance tasks usually elicit adaptive aversive memories. Traumatic
memories are more intense, generalized, inflexible, and resistant to attenuation via …

Is PTSD-phenotype associated with HPA-axis sensitivity? Feedback inhibition and other modulating factors of glucocorticoid signaling dynamics

D Danan, D Todder, J Zohar, H Cohen - International journal of molecular …, 2021 - mdpi.com
Previously, we found that basal corticosterone pulsatility significantly impacts the
vulnerability for developing post-traumatic stress disorder (PTSD). Rats that exhibited PTSD …

The Glucocorticoid Receptor Gene (NR3C1) 9β SNP Is Associated with Posttraumatic Stress Disorder

I Castro-Vale, C Durães, EFC van Rossum… - Healthcare, 2021 - mdpi.com
Posttraumatic stress disorder (PTSD) has been associated with glucocorticoid (GC)
hypersensitivity. Although genetic factors account for 30–46% of the variance in PTSD, no …

The pathways between cortisol-related regulation genes and PTSD psychotherapy

I Castro-Vale, D Carvalho - Healthcare, 2020 - mdpi.com
Post-traumatic stress disorder (PTSD) only develops after exposure to a traumatic event in
some individuals. PTSD can be chronic and debilitating, and is associated with co …