It is a major concern to treat cancer successfully, due to the distinctive pathophysiology of
cancer cells and the gradual manifestation of resistance. Specific action, adverse effects and …

Hydroxycamptothecin (HCPT) is a natural plant alkaloid from Camptotheca that shows
potent antitumor activity by targeting intracellular topoisomerase I. However, factors such as …

Objectives Recently, it has been reported that cepharanthine (CEP) is highly likely to be an
agent against Coronavirus disease 2019 (COVID-19). In the present study, a network …

Coptis chinensis Franch (CCF) has been widely used by Chinese old herbalist doctor to
treat internal and external diseases including malignant sore and cancer. Berberine (BBR) is …

In the current work, the synergy between natural compounds and conventional
chemotherapeutic drugs is comprehensively reviewed in light of current preclinical research …

Background Severe endoplasmic reticulum (ER) stress elicits apoptosis to suppress lung
cancer. Our previous research identified that Cepharanthine (CEP), a kind of phytomedicine …

Unsaturated fat replacement should be used to reduce the use of saturated fat and trans fatty
acids in the diet. In this study, pea protein micro-gels (PPMs) with different structures were …

Protein tyrosine phosphatase non-receptor type 2 (PTPN2) has recently become a viable
target for cancer immunotherapy. Our study aimed to predict compounds with potential to …

Objective: EGFR-TK domain is of great importance in the initiation and progression of
various cancer types, especially lung cancer. The existing EGFR-TK inhibitors have …

It has been established that in developing countries like India, lung cancer is the main
reason of many deaths. There has been worldwide concern about the rising mortality toll …