Abstract The Infectious Diseases Society of America (IDSA) is committed to providing up-to-
date guidance on the treatment of antimicrobial-resistant infections. A previous guidance …

Abstract Purpose This Position Paper aims to review and discuss the available data on
therapeutic drug monitoring (TDM) of antibacterials, antifungals and antivirals in critically ill …

The polymyxin antibiotics colistin (polymyxin E) and polymyxin B became available in the
1950s and thus did not undergo contemporary drug development procedures. Their clinical …

Background: Infections caused by multi-drug-resistant Gram-negative bacteria, particularly
Acinetobacter baumannii, Pseudomonas aeruginosa and Klebsiella pneumoniae, that …

This article provides a comprehensive review of currently available treatment options for
infections due to carbapenem-resistant Enterobacteriaceae (CRE). Antimicrobial resistance …

Background. Intravenous colistin is difficult to use because plasma concentrations for
antibacterial effect overlap those causing nephrotoxicity, and there is large interpatient …

Abstract Background Carbapenem-resistant Acinetobacter baumannii (CRAB) has gained
global notoriety as a critically important nosocomial pathogen. It mostly affects debilitated …

Introduction: In the era of multidrug-resistant, extensively drug-resistant (XDR) and even
pandrug-resistant Gram-negative microorganisms, the medical community is facing the …

Hospital-acquired pneumonia and ventilator-associated pneumo... : Current Opinion in
Pulmonary Medicine Hospital-acquired pneumonia and ventilator-associated pneumonia …

The emergence of carbapenem resistance in Enterobacteriaceae is an important threat to
global health. Reported outcomes of infections with carbapenem-resistant …