[HTML][HTML] Therapeutic potential of flavonoids in cancer: ROS-mediated mechanisms

H Slika, H Mansour, N Wehbe, SA Nasser… - Biomedicine & …, 2022 - Elsevier
Cancer is a leading cause of morbidity and mortality around the globe. Reactive oxygen
species (ROS) play contradicting roles in cancer incidence and progression. Antioxidants …

Therapeutic potential of quercetin: new insights and perspectives for human health

B Salehi, L Machin, L Monzote, J Sharifi-Rad… - ACS …, 2020 - ACS Publications
Quercetin (Que) and its derivatives are naturally occurring phytochemicals with promising
bioactive effects. The antidiabetic, anti-inflammatory, antioxidant, antimicrobial, anti …

[HTML][HTML] Pharmacological basis and new insights of quercetin action in respect to its anti-cancer effects

SM Tang, XT Deng, J Zhou, QP Li, XX Ge… - Biomedicine & …, 2020 - Elsevier
Quercetin is a kind of flavonoid compounds that comes from nature and is widely existed in
the daily diet. Previous studies have found that quercetin has many effects such as anti …

[HTML][HTML] Anticancer and apoptosis‑inducing effects of quercetin in vitro and in vivo

M Hashemzaei, A Delarami Far… - Oncology …, 2017 - … .spandidos-publications.com
The present study focused on the elucidation of the putative anticancer potential of
quercetin. The anticancer activity of quercetin at 10, 20, 40, 80 and 120 µM was assessed in …

[HTML][HTML] Quercetin and cancer: new insights into its therapeutic effects on ovarian cancer cells

A Vafadar, Z Shabaninejad, A Movahedpour, F Fallahi… - Cell & bioscience, 2020 - Springer
Ovarian cancer is known as a serious malignancy that affects women's reproductive tract
and can considerably threat their health. A wide range of molecular mechanisms and …

Topical nanostructured lipid carrier gel of quercetin and resveratrol: Formulation, optimization, in vitro and ex vivo study for the treatment of skin cancer

M Imran, MK Iqubal, K Imtiyaz, S Saleem… - International journal of …, 2020 - Elsevier
The objective of this investigation was to develop dual drug-loaded nanostructured lipid
carrier (NLC) gel of quercetin and resveratrol to enhance their disposition in dermal and …

The involvement of the oxidative stress status in cancer pathology: a double view on the role of the antioxidants

KF Zahra, R Lefter, A Ali, EC Abdellah… - Oxidative Medicine …, 2021 - Wiley Online Library
Oxygen‐free radicals, reactive oxygen species (ROS) or reactive nitrogen species (RNS),
are known by their “double‐sided” nature in biological systems. The beneficial effects of …

[HTML][HTML] Antioxidants of edible mushrooms

M Kozarski, A Klaus, D Jakovljevic, N Todorovic… - Molecules, 2015 - mdpi.com
Oxidative stress caused by an imbalanced metabolism and an excess of reactive oxygen
species (ROS) lead to a range of health disorders in humans. Our endogenous antioxidant …

[HTML][HTML] Potential therapeutic targets of quercetin, a plant flavonol, and its role in the therapy of various types of cancer through the modulation of various cell signaling …

SA Almatroodi, MA Alsahli, A Almatroudi, AK Verma… - Molecules, 2021 - mdpi.com
Polyphenolic flavonoids are considered natural, non-toxic chemopreventers, which are most
commonly derived from plants, fruits, and vegetables. Most of these polyphenolics exhibit …

[HTML][HTML] Effects of sorafenib and quercetin alone or in combination in treating hepatocellular carcinoma: in vitro and in vivo approaches

S Abdu, N Juaid, A Amin, M Moulay, N Miled - Molecules, 2022 - mdpi.com
Sorafenib is the first drug approved to treat advanced hepatocellular carcinoma (HCC) and
continues as the gold-standard therapy against HCC. However, acquired drug resistance …