Sociology, genetics, and the coming of age of sociogenomics

MC Mills, FC Tropf - Annual review of sociology, 2020 - annualreviews.org
Recent years have seen the birth of sociogenomics via the infusion of molecular genetic
data. We chronicle the history of genetics, focusing particularly on post-2005 genome-wide …

Insights from Mendelian randomization and genetic correlation analyses into the relationship between endometriosis and its comorbidities

IM McGrath, GW Montgomery… - Human reproduction …, 2023 - academic.oup.com
BACKGROUND Endometriosis remains a poorly understood disease, despite its high
prevalence and debilitating symptoms. The overlap in symptoms and the increased risk of …

[HTML][HTML] Genome-wide analyses of ADHD identify 27 risk loci, refine the genetic architecture and implicate several cognitive domains

D Demontis, GB Walters, G Athanasiadis, R Walters… - Nature …, 2023 - nature.com
Attention-deficit hyperactivity disorder (ADHD) is a prevalent neurodevelopmental disorder
with a major genetic component. Here, we present a genome-wide association study meta …

CADM2 is implicated in impulsive personality and numerous other traits by genome- and phenome-wide association studies in humans and mice

S Sanchez-Roige, MV Jennings, HHA Thorpe… - Translational …, 2023 - nature.com
Impulsivity is a multidimensional heritable phenotype that broadly refers to the tendency to
act prematurely and is associated with multiple forms of psychopathology, including …

Sex‐specific reproductive factors augment cardiovascular disease risk in women: a Mendelian randomization study

M Ardissino, EAW Slob, P Carter, T Rogne… - Journal of the …, 2023 - Am Heart Assoc
Background Observational studies suggest that reproductive factors are associated with
cardiovascular disease, but these are liable to influence by residual confounding. This study …

Genetic associations with parental investment from conception to wealth inheritance in six cohorts

J Wertz, TE Moffitt, L Arseneault, JC Barnes… - Nature Human …, 2023 - nature.com
Genetic inheritance is not the only way parents' genes may affect children. It is also possible
that parents' genes are associated with investments into children's development. We …

A “one‐stop shop” decision tree for diagnosing and phenotyping polycystic ovarian syndrome on serum metabolic fingerprints

R Wang, Z Gu, Y Wang, X Yin, W Liu… - Advanced Functional …, 2022 - Wiley Online Library
Polycystic ovary syndrome (PCOS) is a common endocrine disease regulated by metabolic
disorders, the effective intervention of which depends on diverse phenotypes (eg, insulin …

Research Review: How to interpret associations between polygenic scores, environmental risks, and phenotypes

JB Pingault, AG Allegrini, T Odigie… - Journal of Child …, 2022 - Wiley Online Library
Background Genetic influences are ubiquitous as virtually all phenotypes and most
exposures typically classified as environmental have been found to be heritable. A …

[HTML][HTML] Rare genetic variants explain missing heritability in smoking

SK Jang, L Evans, A Fialkowski, DK Arnett… - Nature human …, 2022 - nature.com
Common genetic variants explain less variation in complex phenotypes than inferred from
family-based studies, and there is a debate on the source of this 'missing heritability'. We …

Evidence from Finland and Sweden on the relationship between early-life diseases and lifetime childlessness in men and women

A Liu, ET Akimova, X Ding, S Jukarainen… - Nature Human …, 2024 - nature.com
The percentage of people without children over their lifetime is approximately 25% in men
and 20% in women. Individual diseases have been linked to childlessness, mostly in …