Sociology, genetics, and the coming of age of sociogenomics
Recent years have seen the birth of sociogenomics via the infusion of molecular genetic
data. We chronicle the history of genetics, focusing particularly on post-2005 genome-wide …
data. We chronicle the history of genetics, focusing particularly on post-2005 genome-wide …
Insights from Mendelian randomization and genetic correlation analyses into the relationship between endometriosis and its comorbidities
IM McGrath, GW Montgomery… - Human reproduction …, 2023 - academic.oup.com
BACKGROUND Endometriosis remains a poorly understood disease, despite its high
prevalence and debilitating symptoms. The overlap in symptoms and the increased risk of …
prevalence and debilitating symptoms. The overlap in symptoms and the increased risk of …
[HTML][HTML] Genome-wide analyses of ADHD identify 27 risk loci, refine the genetic architecture and implicate several cognitive domains
Attention-deficit hyperactivity disorder (ADHD) is a prevalent neurodevelopmental disorder
with a major genetic component. Here, we present a genome-wide association study meta …
with a major genetic component. Here, we present a genome-wide association study meta …
CADM2 is implicated in impulsive personality and numerous other traits by genome- and phenome-wide association studies in humans and mice
S Sanchez-Roige, MV Jennings, HHA Thorpe… - Translational …, 2023 - nature.com
Impulsivity is a multidimensional heritable phenotype that broadly refers to the tendency to
act prematurely and is associated with multiple forms of psychopathology, including …
act prematurely and is associated with multiple forms of psychopathology, including …
Sex‐specific reproductive factors augment cardiovascular disease risk in women: a Mendelian randomization study
Background Observational studies suggest that reproductive factors are associated with
cardiovascular disease, but these are liable to influence by residual confounding. This study …
cardiovascular disease, but these are liable to influence by residual confounding. This study …
Genetic associations with parental investment from conception to wealth inheritance in six cohorts
Genetic inheritance is not the only way parents' genes may affect children. It is also possible
that parents' genes are associated with investments into children's development. We …
that parents' genes are associated with investments into children's development. We …
A “one‐stop shop” decision tree for diagnosing and phenotyping polycystic ovarian syndrome on serum metabolic fingerprints
R Wang, Z Gu, Y Wang, X Yin, W Liu… - Advanced Functional …, 2022 - Wiley Online Library
Polycystic ovary syndrome (PCOS) is a common endocrine disease regulated by metabolic
disorders, the effective intervention of which depends on diverse phenotypes (eg, insulin …
disorders, the effective intervention of which depends on diverse phenotypes (eg, insulin …
Research Review: How to interpret associations between polygenic scores, environmental risks, and phenotypes
JB Pingault, AG Allegrini, T Odigie… - Journal of Child …, 2022 - Wiley Online Library
Background Genetic influences are ubiquitous as virtually all phenotypes and most
exposures typically classified as environmental have been found to be heritable. A …
exposures typically classified as environmental have been found to be heritable. A …
[HTML][HTML] Rare genetic variants explain missing heritability in smoking
Common genetic variants explain less variation in complex phenotypes than inferred from
family-based studies, and there is a debate on the source of this 'missing heritability'. We …
family-based studies, and there is a debate on the source of this 'missing heritability'. We …
Evidence from Finland and Sweden on the relationship between early-life diseases and lifetime childlessness in men and women
The percentage of people without children over their lifetime is approximately 25% in men
and 20% in women. Individual diseases have been linked to childlessness, mostly in …
and 20% in women. Individual diseases have been linked to childlessness, mostly in …