[HTML][HTML] Flagella-driven motility of bacteria

S Nakamura, T Minamino - Biomolecules, 2019 - mdpi.com
The bacterial flagellum is a helical filamentous organelle responsible for motility. In bacterial
species possessing flagella at the cell exterior, the long helical flagellar filament acts as a …

The ensemble nature of allostery

HN Motlagh, JO Wrabl, J Li, VJ Hilser - Nature, 2014 - nature.com
Allostery is the process by which biological macromolecules (mostly proteins) transmit the
effect of binding at one site to another, often distal, functional site, allowing for regulation of …

Crystal structure of the entire respiratory complex I

R Baradaran, JM Berrisford, GS Minhas, LA Sazanov - Nature, 2013 - nature.com
Complex I is the first and largest enzyme of the respiratory chain and has a central role in
cellular energy production through the coupling of NADH: ubiquinone electron transfer to …

Responding to chemical gradients: bacterial chemotaxis

V Sourjik, NS Wingreen - Current opinion in cell biology, 2012 - Elsevier
Chemotaxis allows bacteria to follow gradients of nutrients and other environmental stimuli.
The bacterium Escherichia coli performs chemotaxis via a run-and-tumble strategy in which …

Estimating entropy production from waiting time distributions

DJ Skinner, J Dunkel - Physical review letters, 2021 - APS
Living systems operate far from thermal equilibrium by converting the chemical potential of
ATP into mechanical work to achieve growth, replication, or locomotion. Given time series …

Signal processing in complex chemotaxis pathways

SL Porter, GH Wadhams, JP Armitage - Nature Reviews Microbiology, 2011 - nature.com
Bacteria use chemotaxis to migrate towards environments that are better for growth.
Chemoreceptors detect changes in attractant levels and signal through two-component …

Improved bounds on entropy production in living systems

DJ Skinner, J Dunkel - … of the National Academy of Sciences, 2021 - National Acad Sciences
Living systems maintain or increase local order by working against the second law of
thermodynamics. Thermodynamic consistency is restored as they consume free energy …

Allostery and the Monod-Wyman-Changeux model after 50 years

JP Changeux - Annual review of biophysics, 2012 - annualreviews.org
The Monod-Wyman-Changeux (MWC) model was conceived in 1965 to account for the
signal transduction and cooperative properties of bacterial regulatory enzymes and …

Structural basis of directional switching by the bacterial flagellum

S Johnson, JC Deme, EJ Furlong, JJE Caesar… - Nature …, 2024 - nature.com
The bacterial flagellum is a macromolecular protein complex that harvests energy from uni-
directional ion flow across the inner membrane to power bacterial swimming via rotation of …

Assembly of the bacterial type III secretion machinery

A Diepold, S Wagner - FEMS microbiology reviews, 2014 - academic.oup.com
Many bacteria that live in contact with eukaryotic hosts, whether as symbionts or as
pathogens, have evolved mechanisms that manipulate host cell behaviour to their benefit …