Intracellular delivery is a key step in biological research and has enabled decades of
biomedical discoveries. It is also becoming increasingly important in industrial and medical …

Malaria has been a major global health problem of humans through history and is a leading
cause of death and disease across many tropical and subtropical countries. Over the last …

Protozoan parasites have developed elaborate motility systems that facilitate infection and
dissemination. For example, amoebae use actin-rich membrane extensions called …

Malaria accounts for an enormous burden of disease globally, with Plasmodium falciparum
accounting for the majority of malaria, and P. vivax being a second important cause …

Microscale thermophoresis (MST) allows for quantitative analysis of protein interactions in
free solution and with low sample consumption. The technique is based on thermophoresis …

During blood stage Plasmodium falciparum infection, merozoites invade uninfected
erythrocytes via a complex, multistep process involving a series of distinct receptor-ligand …

Plasmodium species cause malaria by proliferating in human erythrocytes. Invasion of
immunologically privileged erythrocytes provides a relatively protective niche as well as …

Abstract Apical membrane antigen 1 (AMA1) is a key malaria vaccine candidate and target
of neutralizing antibodies. AMA1 binds to a loop in rhoptry neck protein 2 (RON2L) to form …

Malaria is a major disease of humans caused by protozoan parasites from the genus
Plasmodium. It has a complex life cycle; however, asexual parasite infection within the blood …

To mediate its survival and virulence, the malaria parasite Plasmodium falciparum exports
hundreds of proteins into the host erythrocyte. To enter the host cell, exported proteins must …