Traumatic brain injuries

K Blennow, DL Brody, PM Kochanek, H Levin… - Nature reviews Disease …, 2016 - nature.com
Traumatic brain injuries (TBIs) are clinically grouped by severity: mild, moderate and severe.
Mild TBI (the least severe form) is synonymous with concussion and is typically caused by …

Biomarkers of mild traumatic brain injury in cerebrospinal fluid and blood

H Zetterberg, DH Smith, K Blennow - Nature Reviews Neurology, 2013 - nature.com
Mild traumatic brain injury (TBI), which is defined as a head trauma resulting in a brief loss of
consciousness and/or alteration of mental state, is usually benign, but occasionally causes …

Fluid biomarkers for mild traumatic brain injury and related conditions

H Zetterberg, K Blennow - Nature reviews neurology, 2016 - nature.com
Diagnostic and prognostic biomarkers for mild traumatic brain injury (TBI), also known as
concussion, remain a major unmet clinical need. Moderate to severe TBI can be diagnosed …

Classification of traumatic brain injury for targeted therapies

KE Saatman, AC Duhaime, R Bullock… - Journal of …, 2008 - liebertpub.com
The heterogeneity of traumatic brain injury (TBI) is considered one of the most significant
barriers to finding effective therapeutic interventions. In October, 2007, the National Institute …

[HTML][HTML] Management of severe traumatic brain injury (first 24 hours)

T Geeraerts, L Velly, L Abdennour, K Asehnoune… - … Critical Care & Pain …, 2018 - Elsevier
Abstract The latest French Guidelines for the management in the first 24 hours of patients
with severe traumatic brain injury (TBI) were published in 1998. Due to recent changes …

Early prognosis in traumatic brain injury: from prophecies to predictions

HF Lingsma, B Roozenbeek, EW Steyerberg… - The Lancet …, 2010 - thelancet.com
Traumatic brain injury (TBI) is a heterogeneous condition that encompasses a broad
spectrum of disorders. Outcome can be highly variable, particularly in more severely injured …

Diffuse axonal injury and oxidative stress: a comprehensive review

A Frati, D Cerretani, AI Fiaschi, P Frati, V Gatto… - International journal of …, 2017 - mdpi.com
Traumatic brain injury (TBI) is one of the world's leading causes of morbidity and mortality
among young individuals. TBI applies powerful rotational and translational forces to the …

[HTML][HTML] Cell death and recovery in traumatic brain injury

Y Akamatsu, KA Hanafy - Neurotherapeutics, 2020 - Elsevier
Traumatic brain injury (TBI) is the leading cause of morbidity and mortality worldwide.
Although TBI leads to mechanical damage during initial impact, secondary damage also …

Brain neurotrauma: molecular, neuropsychological, and rehabilitation aspects

FH Kobeissy - 2015 - books.google.com
With the contribution from more than one hundred CNS neurotrauma experts, this book
provides a comprehensive and up-to-date account on the latest developments in the area of …

Ubiquitin C-terminal hydrolase is a novel biomarker in humans for severe traumatic brain injury

L Papa, L Akinyi, MC Liu, JA Pineda… - Critical care …, 2010 - journals.lww.com
Objective: Ubiquitin C-terminal hydrolase (UCH-L1), also called neuronal-specific protein
gene product (PGP 9.3), is highly abundant in neurons. To assess the reliability of UCH-L1 …