[HTML][HTML] Nutraceutical properties of polyphenols against liver diseases

J Simón, M Casado-Andrés, N Goikoetxea-Usandizaga… - Nutrients, 2020 - mdpi.com
Current food tendencies, suboptimal dietary habits and a sedentary lifestyle are spreading
metabolic disorders worldwide. Consequently, the prevalence of liver pathologies is …

[HTML][HTML] Chinese herbal formula ruangan granule enhances the efficacy of entecavir to reverse advanced liver fibrosis/early cirrhosis in patients with chronic HBV …

Y Xing, W Zhong, D Peng, Z Han, H Zeng… - Pharmacological …, 2023 - Elsevier
Background Nucleotide analogs treatment can reverse liver fibrosis in chronic hepatitis B
(CHB). However, it has limited effect on fibrosis resolution in patients with CHB, particularly …

Protective effect of acrocarpus fraxinifolius extract against hepatic fibrosis induced by Gamma irradiation and carbon tetrachloride in albino rats

OE El-Shawi, HAS El-Nashar… - … Journal of Radiation …, 2023 - Taylor & Francis
Purpose Liver fibrosis is considered as one of the ultimate outcomes of chronic liver
disorders, characterized by outrageous cell proliferation and abnormal deposition of …

[HTML][HTML] Bioactive compounds from Actinidia arguta fruit as a new strategy to fight glioblastoma

C Macedo, PC Costa, F Rodrigues - Food Research International, 2023 - Elsevier
In recent years, there has been a significant demand for natural products as a mean of
disease prevention or as an alternative to conventional medications. The driving force for …

[HTML][HTML] Hepatoprotective effect of pinostrobin against thioacetamide-induced liver cirrhosis in rats

SH Shareef, MH Al-Medhtiy, AS Al Rashdi… - Saudi Journal of …, 2023 - Elsevier
The study in vivo assessed the effect of pinostrobin on the histology, immunohistochemistry,
and biochemical parameters of thioacetamide (TAA) induced liver cirrhosis in Sprague …

Gallic acid and ferulic acid protect the liver from thioacetamide-induced fibrosis in rats via differential expression of miR-21, miR-30 and miR-200 and impact on TGF …

RM Hussein, MM Anwar, HS Farghaly… - Chemico-biological …, 2020 - Elsevier
This study evaluates the possible protective effects of gallic acid (GaA) and ferulic acid (FeA)
against an experimentally induced liver fibrosis by thioacetamide (TAA) in rats. Animals …

Zein/phospholipid composite nanoparticles for successful delivery of gallic acid into ahscs: Influence of size, surface charge, and vitamin a coupling

SAA Radwan, WH El-Maadawy, C Yousry… - International journal …, 2020 - Taylor & Francis
Purpose Zein/phospholipid composite nanoparticles (CNPs) were developed as a delivery
platform for gallic acid (GA), a polyphenolic compound with reported preclinical antifibrotic …

[HTML][HTML] The phenylethanol glycoside liposome inhibits PDGF-induced HSC activation via regulation of the FAK/PI3K/Akt signaling pathway

SL Zhang, L Ma, J Zhao, SP You, XT Ma, XY Ye, T Liu - Molecules, 2019 - mdpi.com
Cistanche tubulosa is a traditional Chinese herbal medicine that is widely used to regulate
immunity, and phenylethanol glycosides (CPhGs) are among the primary components …

[HTML][HTML] Gallic acid and metformin co-administration reduce oxidative stress, apoptosis and inflammation via Fas/caspase-3 and NF-κB signaling pathways in …

EK Mohamed, DM Hafez - BMC Complementary Medicine and Therapies, 2023 - Springer
Background Hepatic encephalopathy (HE) is a consequence of chronic or acute liver
diseases. This study evaluates the combined effect of gallic acid (GA), and metformin (Met) …

Impact of reverse micelle loaded lipid nanocapsules on the delivery of gallic acid into activated hepatic stellate cells: a promising therapeutic approach for hepatic …

SAA Radwan, WH El-Maadawy, AN ElMeshad… - Pharmaceutical …, 2020 - Springer
Purpose Gallic acid (GA) is a polyphenolic compound with proven efficacy against hepatic
fibrosis in experimental animals. However, it suffers from poor bioavailability and rapid …