Increasing evidence suggests that infection with Sars-CoV-2 causes neurological deficits in
a substantial proportion of affected patients. While these symptoms arise acutely during the …

MicroRNAs (miRNAs) play a critical role in regulating various biological processes, such as
cell differentiation and immune modulation by binding to their target genes. miR-223 is a …

Necroptosis is the major cause of death in alveolar epithelial cells (AECs) during acute lung
injury (ALI). Here, we report a previously unrecognized mechanism for necroptosis. We …

MicroRNAs were discovered more than 2 decades ago and have profound impact on
diverse biological processes. Specific microRNAs have important roles in modulating the …

Glioblastoma multiforme (GBM) is highly invasive, with a high recurrence rate and limited
treatment options, and is the deadliest glioma. Exosomes (Exos) have attracted much …

MicroRNAs (miRNAs) are diminutive noncoding RNAs that can influence disease
development and progression by post-transcriptionally regulating gene expression. The anti …

Gluconic metabolic reprogramming, immune response, and inflammation are intimately
linked. Glycolysis involves in the pathologic progress in acute and chronic inflammatory …

Millions of COVID-19 patients have succumbed to respiratory and systemic inflammation.
Hyperstimulation of toll-like receptor (TLR) signaling is a key driver of immunopathology …

The innate immune system represents the host's first-line defense against pathogens, dead
cells or environmental factors. One of the most important inflammatory pathways is …

Emodin is a natural occurring anthraquinone derivative isolated from roots and barks of
numerous plants, molds, and lichens. It is found to be an active ingredient in different …