Quantitative MRI provides biophysical measures of the microstructural integrity of the CNS,
which can be compared across CNS regions, patients, and centres. In patients with multiple …

Abstract Purpose of Review For many years, exercise was controversial in multiple sclerosis
(MS) and thought to exacerbate symptoms and fatigue. However, having been found to be …

Profound and debilitating fatigue is the most common complaint reported among individuals
with autoimmune disease, such as systemic lupus erythematosus, multiple sclerosis, type 1 …

Each year about 650,000 Europeans die from stroke and a similar number lives with the
sequelae of multiple sclerosis (MS). Stroke and MS differ in their etiology. Although cause …

Multiple sclerosis (MS) represents the most common acquired demyelinating disorder of the
central nervous system (CNS). Its pathogenesis, in parallel with the well-established role of …

Background: Optical coherence tomography (OCT) angiography is a new method to assess
the density of the vascular networks. Vascular abnormalities are considered involved in …

Following an acute COVID-19 infection, a large number of patients experience persisting
symptoms for more than four weeks, a condition now classified as Long-COVID syndrome …

Retinal microcirculation shares similar features with cerebral small blood vessels. Thus, the
retina may be considered an accessible 'window'to detect the microvascular damage …

Vascular changes are increasingly recognized as important factors in the pathophysiology of
neuroinflammatory disease, especially in multiple sclerosis (MS). The relatively novel …

The deep and periventricular white matter is preferentially affected in several neurological
disorders, including cerebral small vessel disease (SVD) and multiple sclerosis (MS) …