In Duchenne muscular dystrophy, dystrophin loss leads to chronic muscle damage,
dysregulation of repair, fibro-fatty replacement, and weakness. We develop methodology to …

Aims Muscle biopsy techniques range from needle muscle biopsy (NMB) and conchotome
biopsy to open surgical biopsy. It is unknown whether specific biopsy techniques offer …

There are currently no surgical procedures that effectively address the treatment of
volumetric muscle loss (VML) injuries that has motivated the development of implantable …

Pompe disease is a rare glycogen storage disease caused by mutations in the enzyme acid
α‐glucosidase (GAA) resulting in pathological accumulation of glycogen in muscle tissues …

Cerebral palsy (CP) is a heterogeneous group of motor disorders attributed to a non-
progressive lesion in the developing brain. Knowledge on skeletal muscle properties is …

Trends in diagnostic biopsy sample collection approaches for primary bone sarcomas have
shifted in the past 2 decades. Although open/incisional biopsies used to be the predominant …

Abstract Paediatric Interventional Oncology (IO) lags behind adult IO due to a scarcity of
specific outcome data. The suboptimal way to evolve this field is relying heavily on adult …

Introduction Open surgical muscle biopsy has traditionally been required for the histological
diagnosis of myopathy but requires neurosurgical expertise with a variable diagnostic yield …

Background Cervical tuberculous lymphadenitis (CTBL) is a disease often ignored in clinical
work, and pathology and Xpert MTB/RIF (Xpert) are the commonly used methods for …

In vitro models of patient-derived muscle allow for more efficient development of genetic
medicines for the muscular dystrophies, which often present mutation-specific pathologies …