Melatonin is an ancient molecule that can be traced back to the origin of life. Melatonin's
initial function was likely that as a free radical scavenger. Melatonin presumably evolved in …

Melatonin is an ancient antioxidant. After its initial development in bacteria, it has been
retained throughout evolution such that it may be or may have been present in every species …

Melatonin is remarkably functionally diverse with actions as a free radical scavenger and
antioxidant, circadian rhythm regulator, anti‐inflammatory and immunoregulating molecule …

The emergence of OpenAI's ChatGPT has put intense spotlight on Generative AI (Gen-AI)
systems and their possible impacts on Academic integrity. This paper provides an overview …

G protein-coupled receptors (GPCRs) are classically characterized as cell-surface receptors
transmitting extracellular signals into cells. Here we show that central components of a …

Endogenous melatonin is synthesized from tryptophan via 5-hydroxytryptamine. It is
considered an indoleamine from a biochemical point of view because the melatonin …

Melatonin has been speculated to be mainly synthesized by mitochondria. This speculation
is supported by the recent discovery that aralkylamine N-acetyltransferase/serotonin N …

Abstract Melatonin (N‐acetyl‐5‐methoxytryptamine), an indoleamine produced in many
organs including the pineal gland, was initially characterized as a hormone primarily …

Background Melatonin is an indole hormone secreted primarily by the pineal gland that
showing anti-oxidant, anti-inflammatory and anti-apoptotic capacity. It can play an important …

Melatonin is a multifunctional signaling molecule, ubiquitously distributed in different parts of
plants and responsible for stimulating several physiological responses to adverse …