Exposure to chemotherapy during childhood or adulthood and consequences on spermatogenesis and male fertility

M Delessard, J Saulnier, A Rives, L Dumont… - International journal of …, 2020 - mdpi.com
Over the last decade, the number of cancer survivors has increased thanks to progress in
diagnosis and treatment. Cancer treatments are often accompanied by adverse side effects …

Parabens in male infertility—Is there a mitochondrial connection?

RS Tavares, FC Martins, PJ Oliveira… - Reproductive …, 2009 - Elsevier
Parabens are widely used as preservatives in many foods, cosmetics, toiletries, and
pharmaceuticals due to their relatively low toxicity profile and to a long history of safe use …

An update on oxidative stress-mediated organ pathophysiology

K Rashid, K Sinha, PC Sil - Food and chemical toxicology, 2013 - Elsevier
Exposure to environmental pollutants and drugs can result in pathophysiological situations
in the body. Research in this area is essential as the knowledge on cellular survival and …

Propolis attenuates doxorubicin-induced testicular toxicity in rats

SM Rizk, HF Zaki, MAM Mina - Food and chemical toxicology, 2014 - Elsevier
Doxorubicin (Dox), an effective anticancer agent, can impair testicular function leading to
infertility. The present study aimed to explore the protective effect of propolis extract on Dox …

Kaempferol protects against doxorubicin-induced cardiotoxicity in vivo and in vitro

J Xiao, GB Sun, B Sun, Y Wu, L He, X Wang, RC Chen… - Toxicology, 2012 - Elsevier
The long-term clinical usefulness of doxorubicin (DOX), an anthracycline with potent
antitumor activity, is limited by DOX-induced cardiotoxicity. Kaempferol, one of the most …

Minocycline can reduce testicular apoptosis related to varicocele in male rats

M Shokoohi, A Khaki, A Roudi Rasht Abadi… - Andrologia, 2022 - Wiley Online Library
The current research aimed to assess the impacts of Minocycline on varicocele‐induced
regulation of apoptotic‐related genes and oxidative stress in the testis of adult Wistar rats …

Recent advances in protection against doxorubicin-induced toxicity

R Injac, B Strukelj - Technology in cancer research & …, 2008 - journals.sagepub.com
Anthracycline antibiotics are among the most effective and commonly used anticancer
drugs. Unfortunately, their clinical use is restricted by dose-dependent toxicity. Doxorubicin …

Taurine protects rat testes against doxorubicin-induced oxidative stress as well as p53, Fas and caspase 12-mediated apoptosis

J Das, J Ghosh, P Manna, PC Sil - Amino acids, 2012 - Springer
The protective effect of taurine against doxorubicin-induced testicular oxidative stress and
apoptosis was investigated in rats. Male rats 8 weeks of age were treated with doxorubicin …

Protective effect of berberine on doxorubicin‑induced acute hepatorenal toxicity in rats

X Chen, Y Zhang, Z Zhu, H Liu… - Molecular …, 2016 - spandidos-publications.com
Doxorubicin (DOX), a potent broad‑spectrum chemotherapeutic agent used for the treatment
of several types of cancer, is largely limited due to its serious side effects on non‑target …

Mechanisms of doxorubicin-mediated reproductive toxicity–a review

UP Mohan, TP PB, STA Iqbal, S Arunachalam - Reproductive Toxicology, 2021 - Elsevier
The anticancer drug doxorubicin has been associated with several adverse side-effects
including reproductive toxicity in both genders. The current review has complied the …