Until recently, erectile dysfunction (ED) was treated by either sexual counseling or penile
prosthesis implantation. The advent of intracavernous and transurethral agents has …

Erection is basically a spinal reflex that can be initiated by recruitment of penile afferents,
both autonomic and somatic, and supraspinal influences from visual, olfactory, and …

Diabetes and urologic diseases are very common health problems that markedly increase in
prevalence and incidence with advancing age (1–3). Diabetes is associated with an earlier …

Purpose: Urinary incontinence and overactive bladder are important and common
conditions that have received little general medical attention. We reviewed the magnitude …

Aging is the main risk factor for coronary artery disease. One characteristic of aging coronary
arteries is their enhanced contractile responses to endothelial vasoconstricting factors …

Nitric oxide (NO), a mediator involved in penile erection, is synthesized by the nitric oxide
synthase (NOS) family of enzymes. It has been shown that NOS activity decreases with age …

Purpose: Our objective was to assess erectile function in saline-injected, transforming
growth factor-beta 1 (TGF-β1)-injected, and surgical injury rats after six weeks and to …

Large conductance Ca2+-activated K+ (BKCa) channels are abundantly expressed in
vascular smooth muscle cells. Activation of BKCa channels leads to hyperpolarization of cell …

Eleven patients with moderate to severe erectile dysfunction (ED) were given a single-dose
corpus cavernosum injection of h Maxi-K, a" naked" DNA plasmid carrying the human cDNA …

Erectile dysfunction (ED) is defined as the consistent inability to obtain or maintain an
erection for satisfactory sexual relations. An estimated 20–30 million men suffer from some …