[HTML][HTML] miRNA: a promising therapeutic target in cancer
microRNAs are small non-coding RNAs that regulate several genes post-transcriptionally by
complementarity pairing. Since discovery, they have been reported to be involved in a …
complementarity pairing. Since discovery, they have been reported to be involved in a …
Decoding the role of miRNAs in multiple myeloma pathogenesis: a focus on signaling pathways
AM Yehia, EGE Elsakka, AI Abulsoud… - … -Research and Practice, 2023 - Elsevier
Multiple myeloma (MM) is a cancer of plasma cells that has been extensively studied in
recent years, with researchers increasingly focusing on the role of microRNAs (miRNAs) in …
recent years, with researchers increasingly focusing on the role of microRNAs (miRNAs) in …
MicroRNA: function, detection, and bioanalysis
Mature microRNAs (miRNAs) are a class of evolutionally conserved, single-stranded, small
(approximately 19− 23 nucleotides), endogenously expressed, and non-protein-coding …
(approximately 19− 23 nucleotides), endogenously expressed, and non-protein-coding …
[HTML][HTML] A hybrid CNN-LSTM model for pre-miRNA classification
A Tasdelen, B Sen - Scientific reports, 2021 - nature.com
Abstract miRNAs (or microRNAs) are small, endogenous, and noncoding RNAs construct of
about 22 nucleotides. Cumulative evidence from biological experiments shows that miRNAs …
about 22 nucleotides. Cumulative evidence from biological experiments shows that miRNAs …
MicroRNA history: discovery, recent applications, and next frontiers
Since 1993, when the first small non-coding RNA was identified, our knowledge about
microRNAs has grown exponentially. In this review, we focus on the main progress in this …
microRNAs has grown exponentially. In this review, we focus on the main progress in this …
MicroRNA-small molecule association identification: from experimental results to computational models
Small molecule is a kind of low molecular weight organic compound with variety of
biological functions. Studies have indicated that small molecules can inhibit a specific …
biological functions. Studies have indicated that small molecules can inhibit a specific …
Design of multifunctional non-viral gene vectors to overcome physiological barriers: dilemmas and strategies
T Wang, JR Upponi, VP Torchilin - International journal of pharmaceutics, 2012 - Elsevier
Gene-based therapeutics hold great promise for medical advancement and have been used
to treat various human diseases with mixed success. However, their therapeutic application …
to treat various human diseases with mixed success. However, their therapeutic application …
Cadmium induces ferroptosis and apoptosis by modulating miR‐34a‐5p/Sirt1axis in PC12 cells
R Hao, J Ge, X Song, F Li… - Environmental …, 2022 - Wiley Online Library
Cadmium (Cd) is a potent neurotoxic metal present in the environment and food. In this
study, CdCl2 (2 or 4 μM) induced cytotoxicity and neurotoxicity in PC12 cells, causing …
study, CdCl2 (2 or 4 μM) induced cytotoxicity and neurotoxicity in PC12 cells, causing …
The oncogenic and tumour suppressive roles of microRNAs in cancer and apoptosis
S Babashah, M Soleimani - European journal of cancer, 2011 - Elsevier
MicroRNAs (miRNAs) are small, non-coding, endogenous RNAs that regulate gene
expression at the post-transcriptional level. MiRNAs play important roles in regulating a …
expression at the post-transcriptional level. MiRNAs play important roles in regulating a …
Identification of microRNA precursor with the degenerate K-tuple or Kmer strategy
The microRNA (miRNA), a small non-coding RNA molecule, plays an important role in
transcriptional and post-transcriptional regulation of gene expression. Its abnormal …
transcriptional and post-transcriptional regulation of gene expression. Its abnormal …