MMP‐9 in translation: from molecule to brain physiology, pathology, and therapy
B Vafadari, A Salamian… - Journal of …, 2016 - Wiley Online Library
Abstract Matrix metalloproteinase‐9 (MMP‐9) is a member of the metzincin family of mostly
extracellularly operating proteases. Despite the fact that all of these enzymes might be target …
extracellularly operating proteases. Despite the fact that all of these enzymes might be target …
Matrix metalloproteinase 9 in epilepsy: the role of neuroinflammation in seizure development
E Bronisz… - Mediators of inflammation, 2016 - Wiley Online Library
Matrix metalloproteinase 9 is a proteolytic enzyme which is recently one of the more often
studied biomarkers. Its possible use as a biomarker of neuronal damage in stroke, heart …
studied biomarkers. Its possible use as a biomarker of neuronal damage in stroke, heart …
Activation of the 5-HT7 receptor and MMP-9 signaling module in the hippocampal CA1 region is necessary for the development of depressive-like behavior
Major depressive disorder is a complex disease resulting from aberrant synaptic plasticity
that may be caused by abnormal serotonergic signaling. Using a combination of behavioral …
that may be caused by abnormal serotonergic signaling. Using a combination of behavioral …
Serotonin 5‐HT 7 receptor increases the density of dendritic spines and facilitates synaptogenesis in forebrain neurons
Precise control of dendritic spine density and synapse formation is critical for normal and
pathological brain functions. Therefore, signaling pathways influencing dendrite outgrowth …
pathological brain functions. Therefore, signaling pathways influencing dendrite outgrowth …
Quantification of dendritic spines remodeling under physiological stimuli and in pathological conditions
Numerous brain diseases are associated with abnormalities in morphology and density of
dendritic spines, small membranous protrusions whose structural geometry correlates with …
dendritic spines, small membranous protrusions whose structural geometry correlates with …
The many roles of dystroglycan in nervous system development and function: Dystroglycan and neural circuit development
JN Jahncke, KM Wright - Developmental Dynamics, 2023 - Wiley Online Library
The glycoprotein dystroglycan was first identified in muscle, where it functions as part of the
dystrophin glycoprotein complex to connect the extracellular matrix to the actin cytoskeleton …
dystrophin glycoprotein complex to connect the extracellular matrix to the actin cytoskeleton …
Serotonin 5-HT4 receptor boosts functional maturation of dendritic spines via RhoA-dependent control of F-actin
Activity-dependent remodeling of excitatory connections underpins memory formation in the
brain. Serotonin receptors are known to contribute to such remodeling, yet the underlying …
brain. Serotonin receptors are known to contribute to such remodeling, yet the underlying …
Control of astrocyte morphology by Rho GTPases
Astrocytes modulate and support neuronal and synapse function via numerous mechanisms
that often rely on diffusion of signalling molecules, ions or metabolites through extracellular …
that often rely on diffusion of signalling molecules, ions or metabolites through extracellular …
MMP-9 signaling pathways that engage rho GTPases in brain plasticity
I Figiel, PK Kruk, M Zaręba-Kozioł, P Rybak, M Bijata… - Cells, 2021 - mdpi.com
The extracellular matrix (ECM) has been identified as a critical factor affecting synaptic
function. It forms a functional scaffold that provides both the structural support and the …
function. It forms a functional scaffold that provides both the structural support and the …
[HTML][HTML] Recent advances in branching mechanisms underlying neuronal morphogenesis
Proper neuronal wiring is central to all bodily functions, sensory perception, cognition,
memory, and learning. Establishment of a functional neuronal circuit is a highly regulated …
memory, and learning. Establishment of a functional neuronal circuit is a highly regulated …