Early childhood adversity, toxic stress, and the impacts of racism on the foundations of health

JP Shonkoff, N Slopen… - Annual Review of Public …, 2021 - annualreviews.org
Inequalities in health outcomes impose substantial human and economic costs on all
societies—and the relation between early adversity and lifelong well-being presents a rich …

Adverse cardiac remodelling after acute myocardial infarction: old and new biomarkers

AE Berezin, AA Berezin - Disease Markers, 2020 - Wiley Online Library
The prevalence of heart failure (HF) due to cardiac remodelling after acute myocardial
infarction (AMI) does not decrease regardless of implementation of new technologies …

The lifelong effects of early childhood adversity and toxic stress

JP Shonkoff, AS Garner… - …, 2012 - publications.aap.org
This Technical Report was retired November 2021. Advances in fields of inquiry as diverse
as neuroscience, molecular biology, genomics, developmental psychology, epidemiology …

Leveraging the biology of adversity to address the roots of disparities in health and development

JP Shonkoff - Proceedings of the National Academy of …, 2012 - National Acad Sciences
Extensive evidence that personal experiences and environmental exposures are embedded
biologically (for better or for worse) and the cumulative knowledge of more than four …

Multiple biomarkers for risk prediction in chronic heart failure

B Ky, B French, WC Levy, NK Sweitzer… - Circulation: Heart …, 2012 - Am Heart Assoc
Background—Prior studies have suggested using a panel of biomarkers that measure
diverse biological processes as a prognostic tool in chronic heart failure. Whether this …

Inflammatory activation: cardiac, renal, and cardio-renal interactions in patients with the cardiorenal syndrome

PC Colombo, A Ganda, J Lin, D Onat, A Harxhi… - Heart failure …, 2012 - Springer
Although inflammation is a physiologic response designed to protect us from infection, when
unchecked and ongoing it may cause substantial harm. Both chronic heart failure (CHF) and …

Enhanced interleukin-1 activity contributes to exercise intolerance in patients with systolic heart failure

BW Van Tassell, RA Arena, S Toldo, E Mezzaroma… - PloS one, 2012 - journals.plos.org
Background Heart failure (HF) is a complex clinical syndrome characterized by impaired
cardiac function and poor exercise tolerance. Enhanced inflammation is associated with …

Novel biomarkers of heart failure

A Savic-Radojevic, M Pljesa-Ercegovac, M Matic… - Advances in clinical …, 2017 - Elsevier
Although substantial improvements have been made in majority of cardiac disorders, heart
failure (HF) remains a major health problem, with both increasing incidence and prevalence …

High-sensitivity C-reactive protein in chronic heart failure: patient characteristics, phenotypes, and mode of death

P Pellicori, J Zhang, J Cuthbert, A Urbinati… - Cardiovascular …, 2020 - academic.oup.com
Aims Plasma concentrations of high-sensitivity C-reactive protein (hsCRP) are often raised
in chronic heart failure (CHF) and might indicate inflammatory processes that could be a …

Pilot randomized study of a gratitude journaling intervention on heart rate variability and inflammatory biomarkers in patients with stage B heart failure

LS Redwine, BL Henry, MA Pung, K Wilson… - Psychosomatic …, 2016 - journals.lww.com
Objective Stage B, asymptomatic heart failure (HF) presents a therapeutic window for
attenuating disease progression and development of HF symptoms, and improving quality of …