Molecular mechanisms behind the biological effects of hesperidin and hesperetin for the prevention of cancer and cardiovascular diseases

A Roohbakhsh, H Parhiz, F Soltani, R Rezaee… - Life sciences, 2015 - Elsevier
Hesperidin (Hsd) and its aglycone, hesperetin (Hst), are two flavonoids from citrus species
that have various biological properties, particularly those for the prevention of cancer and …

The role of phenolic compounds in the fight against cancer–a review

M Carocho, I CFR Ferreira - Anti-Cancer Agents in Medicinal …, 2013 - ingentaconnect.com
Cancer is a worldwide scourge; it's the leading cause of death in developed countries and is
increasing in developing countries. Mankind has been trying with effort to find better and …

Hesperidin, a bioflavonoid in cancer therapy: a review for a mechanism of action through the modulation of cell signaling pathways

AH Rahmani, AY Babiker, S Anwar - Molecules, 2023 - mdpi.com
Cancer represents one of the most frequent causes of death in the world. The current
therapeutic options, including radiation therapy and chemotherapy, have various adverse …

Phytochemistry and bioactivity of Citrus flavonoids: a focus on antioxidant, anti-inflammatory, anticancer and cardiovascular protection activities

L Yi, S Ma, D Ren - Phytochemistry Reviews, 2017 - Springer
Epidemiological studies have suggested an inverse relationship between increased
consumption of fruits and reduced risk of chronic diseases, such as cardiovascular diseases …

Application of nano/microencapsulated phenolic compounds against cancer

S Rahaiee, E Assadpour, AF Esfanjani, AS Silva… - Advances in colloid and …, 2020 - Elsevier
Nowadays, polyphenols as bioactive compounds are being used in producing anti-cancer
drugs. Low stability against harsh environmental conditions, untargeted release, low …

Assessment of antioxidant, anti-inflammatory, anti-cholinesterase and cytotoxic activities of pomegranate (Punica granatum) leaves

J Bekir, M Mars, JP Souchard, J Bouajila - Food and chemical toxicology, 2013 - Elsevier
This study evaluated antioxidant, anti-inflammatory, anti-cholinesterase and cytotoxic
activities of extracts with different polarities (hexane, dichloromethane, ethyl acetate, ethanol …

Phenolic compounds as nutraceuticals or functional food ingredients

C Caleja, A Ribeiro… - Current …, 2017 - ingentaconnect.com
Background: Nowadays, the functional foods represent one the most promising, interesting
and innovative areas in the food industry. Various components are being added to foods in …

Hesperidin: A promising anticancer agent from nature

KP Devi, T Rajavel, SF Nabavi, WN Setzer… - Industrial crops and …, 2015 - Elsevier
Cancer is major health problem in the worldwide which refers to a group of diseases caused
by abnormal cell growth with invasive potentials. There are different environmental and …

Therapeutic potential of hesperidin and its aglycone hesperetin: Cell cycle regulation and apoptosis induction in cancer models

JMPF de Oliveira, C Santos, E Fernandes - Phytomedicine, 2020 - Elsevier
Background The ability of cancer cells to divide without restriction and to escape
programmed cell death is a feature of the proliferative state. Citrus flavanones are flavonoids …

Citrus reticulata Blanco peels as a source of antioxidant and anti-proliferative phenolic compounds

SS Ferreira, AM Silva, FM Nunes - Industrial Crops and Products, 2018 - Elsevier
Citrus reticulata Blanco industrial use worldwide generates millions of tons of by-products,
mainly peels, with negative environmental impact. The main purpose of this work was to …