Recent advances in the application of parahydrogen in catalysis and biochemistry

G Buntkowsky, F Theiss, J Lins, YA Miloslavina… - RSC …, 2022 - pubs.rsc.org
Nuclear Magnetic Resonance (NMR) spectroscopy and Magnetic Resonance Imaging (MRI)
are analytical and diagnostic tools that are essential for a very broad field of applications …

Heterogeneous Catalysis and Parahydrogen‐Induced Polarization

EV Pokochueva, DB Burueva, OG Salnikov… - …, 2021 - Wiley Online Library
Parahydrogen‐induced polarization with heterogeneous catalysts (HET‐PHIP) has been a
subject of extensive research in the last decade since its first observation in 2007. While …

Instrumentation for hydrogenative parahydrogen-based hyperpolarization techniques

AB Schmidt, CR Bowers, K Buckenmaier… - Analytical …, 2022 - ACS Publications
The unique properties of the entangled, antisymmetric nuclear spin state of dihydrogen,
parahydrogen (pH2), has intrigued physicists, chemists, and other scientists for almost a …

Ultra-low-cost disposable hand-held clinical-scale propane gas hyperpolarizer for pulmonary magnetic resonance imaging sensing

NM Ariyasingha, A Samoilenko, JR Birchall… - ACS …, 2023 - ACS Publications
Hyperpolarized magnetic resonance imaging (MRI) contrast agents are revolutionizing the
field of biomedical imaging. Hyperpolarized Xe-129 was recently FDA approved as an …

Clinical-scale production of nearly pure (> 98.5%) parahydrogen and quantification by benchtop NMR spectroscopy

S Nantogma, B Joalland, K Wilkens… - Analytical …, 2021 - ACS Publications
Because of the extensive chemical, physical, and biomedical applications of parahydrogen,
the need exists for the development of highly enriched parahydrogen in a robust and …

Parahydrogen‐Induced Hyperpolarization of Gases

KV Kovtunov, IV Koptyug, M Fekete… - Angewandte Chemie …, 2020 - Wiley Online Library
Imaging of gases is a major challenge for any modality including MRI. NMR and MRI signals
are directly proportional to the nuclear spin density and the degree of alignment of nuclear …

High-Pressure Clinical-Scale 87% Parahydrogen Generator

JR Birchall, AM Coffey, BM Goodson… - Analytical …, 2020 - ACS Publications
We present an automated parahydrogen generator (ParaSun) for clinical-scale applications
in parahydrogen-induced polarization (PHIP) and signal amplification by reversible …

Selective filtration of NMR signals arising from weakly-and strongly-coupled spin systems

J Lu, A Jerschow, DE Korenchan - Journal of Magnetic Resonance, 2023 - Elsevier
Nuclear magnetic resonance (NMR) spectroscopy is a powerful technique for analyzing
chemical and biological systems. However, in complex solutions with similar molecular …

Catalytic hydrogenation with parahydrogen: a bridge from homogeneous to heterogeneous catalysis

KV Kovtunov, OG Salnikov, IV Skovpin… - Pure and Applied …, 2020 - degruyter.com
One of the essential themes in modern catalysis is that of bridging the gap between its
homogeneous and heterogeneous counterparts to combine their individual advantages and …

Adaptable singlet-filtered nuclear magnetic resonance spectroscopy for chemical and biological applications

C Huang, Y Peng, E Lin, Z Ni, X Lin, H Zhan… - Analytical …, 2022 - ACS Publications
Proton nuclear magnetic resonance (1H NMR) spectroscopy presents a powerful detection
tool for studying chemical compositions and molecular structures. In practical chemical and …