The 2008 WHO classification of lymphoid neoplasms and beyond: evolving concepts and practical applications

E Campo, SH Swerdlow, NL Harris… - Blood, The Journal …, 2011 - ashpublications.org
Abstract The World Health Organization classification of lymphoid neoplasms updated in
2008 represents a worldwide consensus on the diagnosis of these tumors and is based on …

Diagnosis and classification of hematologic malignancies on the basis of genetics

J Taylor, W Xiao, O Abdel-Wahab - Blood, The Journal of the …, 2017 - ashpublications.org
Genomic analysis has greatly influenced the diagnosis and clinical management of patients
affected by diverse forms of hematologic malignancies. Here, we review how genetic …

Molecular high-grade B-cell lymphoma: defining a poor-risk group that requires different approaches to therapy

C Sha, S Barrans, F Cucco, MA Bentley… - Journal of Clinical …, 2019 - ascopubs.org
Purpose Biologic heterogeneity is a feature of diffuse large B-cell lymphoma (DLBCL), and
the existence of a subgroup with poor prognosis and phenotypic proximity to Burkitt …

Concurrent expression of MYC and BCL2 in diffuse large B-cell lymphoma treated with rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisone

NA Johnson, GW Slack, KJ Savage… - Journal of clinical …, 2012 - ascopubs.org
Purpose Diffuse large B-cell lymphoma (DLBCL) is curable in 60% of patients treated with
rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP). MYC …

MYC/BCL2 protein coexpression contributes to the inferior survival of activated B-cell subtype of diffuse large B-cell lymphoma and demonstrates high-risk gene …

S Hu, ZY Xu-Monette, A Tzankov… - Blood, The Journal …, 2013 - ashpublications.org
Diffuse large B-cell lymphoma (DLBCL) is stratified into prognostically favorable germinal
center B-cell (GCB)–like and unfavorable activated B-cell (ABC)–like subtypes based on …

Immunohistochemical double-hit score is a strong predictor of outcome in patients with diffuse large B-cell lymphoma treated with rituximab plus cyclophosphamide …

TM Green, KH Young, C Visco… - Journal of clinical …, 2012 - ascopubs.org
Purpose Approximately 5% of diffuse large B-cell lymphomas (DLBCLs) are double-hit
lymphomas (DHLs) with translocations of both MYC and BCL2. DHLs are characterized by …

MYC status in concert with BCL2 and BCL6 expression predicts outcome in diffuse large B-cell lymphoma

H Horn, M Ziepert, C Becher, TFE Barth… - Blood, The Journal …, 2013 - ashpublications.org
MYC rearrangements occur in 5% to 10% of diffuse large B-cell lymphomas (DLBCL) and
confer an increased risk to cyclophosphamide, hydroxydaunorubicin, oncovin, and …

Diffuse large B-cell lymphoma—treatment approaches in the molecular era

M Roschewski, LM Staudt, WH Wilson - Nature reviews Clinical …, 2014 - nature.com
Diffuse large B-cell lymphoma (DLBCL) is an aggressive B-cell non-Hodgkin lymphoma that
affects patients of all ages with a wide range of clinical presentations. Although DLBCL is …

Double hit lymphoma: the MD A nderson C ancer C enter clinical experience

Y Oki, M Noorani, P Lin, RE Davis… - British journal of …, 2014 - Wiley Online Library
We report our experience with 129 cases of double hit lymphoma (DHL), defined as B‐cell
lymphoma with translocations and/or extra signals involving MYC plus BCL 2 and/or BCL 6 …

[PDF][PDF] WHO classification of tumours of haematopoietic and lymphoid tissues in 2008: an overview

E Sabattini, F Bacci, C Sagramoso, SA Pileri - Pathologica, 2010 - researchgate.net
Lastly, this edition deserves special attention due to its emphasis on LP related to pathogens
and/or arising in the context of acquired immune suppression. Following, we will briefly …