Gastric cancer is the third leading cause of cancer-related deaths and ranks as the fifth most
common cancer worldwide. Incidence and mortality differ depending on the geographical …

Gastric cancer is of major importance world-wide being the second most common cause of
cancer-related death in the world. According to Lauren's histological classification gastric …

This book is the third volume of the 4th Edition of the WHO series on histological and genetic
typing of human tumours. It is an authoritative, concise reference book providing an …

Mathematical modeling, analysis and simulation are set to play crucial roles in explaining
tumor behavior, and the uncontrolled growth of cancer cells over multiple time and spatial …

Background Intra-tumor heterogeneity is a potential cause for failure of targeted therapy in
gastric cancer, but the extent of heterogeneity of established (HER2) or potential (EGFR …

Epigenetic alterations contribute significantly to the development and progression of gastric
cancer, one of the leading causes of cancer death worldwide. Epigenetics refers to the …

MYC is an oncogene involved in cell cycle regulation, cell growth arrest, cell adhesion,
metabolism, ribosome biogenesis, protein synthesis, and mitochondrial function. It has been …

Background MYC deregulation is a common event in gastric carcinogenesis, usually as a
consequence of gene amplification, chromosomal translocations, or posttranslational …

Our study investigated the relationship between MYC alterations and clinicopathological
features in gastric cancers. We evaluated the effect of MYC mRNA expression and its protein …

The upregulation or mutation of C-MYC has been observed in gastric, colon, breast, and
lung tumors and in Burkitt's lymphoma. However, little is known about the role C-MYC plays …