Fundus-controlled perimetry (FCP, also called 'microperimetry') allows for spatially-resolved
mapping of visual sensitivity and measurement of fixation stability, both in clinical practice as …

Diabetic retinal disease (DRD), the most common complication of diabetes and a leading
cause of blindness in working age individuals, is now understood to be a form of sensory …

Purpose To provide an image-based description of retinal features associated with risk for
development of geographic atrophy (GA) in eyes with age-related macular degeneration …

Purpose Ultrahigh resolution spectral domain-OCT (UHR SD-OCT) enables in vivo
visualization of micrometric structural markers which differentially associate with normal …

Purpose We evaluate the impact of test target location in assessing rod-mediated dark
adaptation (RMDA) along the transition from normal aging to intermediate age-related …

Endpoint development trials are underway across the spectrum of retinal disease. New
validated endpoints are urgently required for the assessment of emerging gene therapies …

Age-related macular degeneration (AMD) is a leading cause of severe vision loss
worldwide, with a global prevalence that is predicted to substantially increase. Identifying …

Purpose: We hypothesize the first visual dysfunction in transitioning to early and
intermediate age-related macular degeneration (AMD) is delayed rod-mediated dark …

Purpose Photoreceptor (PR) outer segments, retinal pigment epithelium apical processes,
and inter-PR matrix contribute to the interdigitation zone (IZ) of optical coherence …

Purpose To examine disease progression in age-related macular degeneration (AMD) at 2
distinct stages, progression to geographic atrophy (GA) versus GA expansion, by …