Acrylamide in food: Occurrence, metabolism, molecular toxicity mechanism and detoxification by phytochemicals
F Yan, L Wang, L Zhao, C Wang, Q Lu, R Liu - Food and Chemical …, 2023 - Elsevier
Acrylamide (ACR) is a common pollutant formed during food thermal processing such as
frying, baking and roasting. ACR and its metabolites can cause various negative effects on …
frying, baking and roasting. ACR and its metabolites can cause various negative effects on …
Protective effects of morin against acrylamide-induced hepatotoxicity and nephrotoxicity: A multi-biomarker approach
Acrylamide (ACR) is a heat-induced carcinogen substance that is found in some foods due
to cooking or other thermal processes. The aim of present study was to assess the probable …
to cooking or other thermal processes. The aim of present study was to assess the probable …
Morin protects against acrylamide-induced neurotoxicity in rats: an investigation into different signal pathways
The presented study investigates the effects of morin against toxicity induced by acrylamide
(ACR) in the brains of Sprague Dawley rats. In this study, neurotoxicity was induced by orally …
(ACR) in the brains of Sprague Dawley rats. In this study, neurotoxicity was induced by orally …
Molecular signaling pathways in doxorubicin-induced nephrotoxicity and potential therapeutic agents
C Lu, J Wei, C Gao, M Sun, D Dong, Z Mu - International …, 2025 - Elsevier
Doxorubicin (DOX), an anthracycline chemotherapeutic agent, is extensively utilized in the
clinical management of both solid and hematological malignancies. Nevertheless, the …
clinical management of both solid and hematological malignancies. Nevertheless, the …
[HTML][HTML] Eriodictyol attenuates doxorubicin-induced nephropathy by activating the AMPK/Nrf2 signalling pathway
RM Badi, EF Khaleel, HH Satti, R Monir - Journal of Traditional and …, 2024 - Elsevier
Doxorubicin (DOX), an anthracycline chemotherapy, plays a prominent role in the treatment
of various cancers. Unfortunately, its nephrotoxic effects limit its dosing and expose cancer …
of various cancers. Unfortunately, its nephrotoxic effects limit its dosing and expose cancer …
Acylated ghrelin protects against doxorubicin‐induced nephropathy by activating silent information regulator 1
AA Shati, AF El‐Kott - Basic & Clinical Pharmacology & …, 2021 - Wiley Online Library
This study investigated the nephroprotective role of acylated ghrelin (AG) against DOX‐
induced nephropathy and examined whether the protection involves silent information …
induced nephropathy and examined whether the protection involves silent information …
Ginkgo Biloba Extract Alleviates Methotrexate-Induced Renal Injury: New Impact on PI3K/Akt/mTOR Signaling and MALAT1 Expression
Renal injury induced by the chemotherapeutic agent methotrexate (MTX) is a serious
adverse effect that has limited its use in the treatment of various clinical conditions. The …
adverse effect that has limited its use in the treatment of various clinical conditions. The …
The therapeutic effect of hesperetin on doxorubicin-induced testicular toxicity: Potential roles of the mechanistic target of rapamycin kinase (mTOR) and dynamin …
Clinical utilization of doxorubicin (DOX), which is a commonly used chemotherapeutic, is
restricted due to toxic effects on various tissues. Using hesperetin (HST), an antioxidant …
restricted due to toxic effects on various tissues. Using hesperetin (HST), an antioxidant …
[HTML][HTML] Irbesartan ameliorates inflammation via transendothelial leukocyte migration due to VCAM-1/NOX-1 signaling in cisplatin-induced cardiotoxicity
DU Karatopuk, S Özkula, E Aydoğdu… - Iranian Journal of …, 2023 - ncbi.nlm.nih.gov
Objective (s): Cisplatin (CP) is frequently used in various types of cancers. The cardiotoxic
effects of this agent limit its usage. Our study seeks to investigate the protective effects of …
effects of this agent limit its usage. Our study seeks to investigate the protective effects of …
Autophagy modulation by irbesartan mitigates the pulmonary fibrotic alterations in bleomycin challenged rats: Comparative study with rapamycin
HA Alsayed, HMF Mohammad, CM Khalil… - Life Sciences, 2022 - Elsevier
Aims In pulmonary fibrosis, autophagy handles the maintenance of alveolar epithelial cells,
prevents epithelial-mesenchymal transition (EMT), and controls collagen turnover. The …
prevents epithelial-mesenchymal transition (EMT), and controls collagen turnover. The …