High-density lipoproteins during sepsis: from bench to bedside

S Tanaka, D Couret, A Tran-Dinh, J Duranteau… - Critical Care, 2020 - Springer
High-density lipoproteins (HDLs) represent a family of particle characterized by the
presence of apolipoprotein AI (apoA-I) and by their ability to transport cholesterol from …

Apolipoprotein C1: its pleiotropic effects in lipid metabolism and beyond

EV Fuior, AV Gafencu - International journal of molecular sciences, 2019 - mdpi.com
Apolipoprotein C1 (apoC1), the smallest of all apolipoproteins, participates in lipid transport
and metabolism. In humans, APOC1 gene is in linkage disequilibrium with APOE gene on …

Altered high-density lipoprotein composition and functions during severe COVID-19

F Begue, S Tanaka, Z Mouktadi, P Rondeau… - Scientific reports, 2021 - nature.com
Abstract Coronavirus disease 2019 (COVID-19) pandemic is affecting millions of patients
worldwide. The consequences of initial exposure to SARS-CoV-2 go beyond pulmonary …

[HTML][HTML] Mortality risk profiling of Staphylococcus aureus bacteremia by multi-omic serum analysis reveals early predictive and pathogenic signatures

JM Wozniak, RH Mills, J Olson, JR Caldera… - Cell, 2020 - cell.com
Staphylococcus aureus bacteremia (SaB) causes significant disease in humans, carrying
mortality rates of∼ 25%. The ability to rapidly predict SaB patient responses and guide …

Lipid profile features and their associations with disease severity and mortality in patients with COVID-19

JT Sun, Z Chen, P Nie, H Ge, L Shen, F Yang… - Frontiers in …, 2020 - frontiersin.org
Background: Emerging studies have described and analyzed epidemiological, clinical,
laboratory, and radiological features of COVID-19 patients. Yet, scarce information is …

Low circulatory levels of total cholesterol, HDL-C and LDL-C are associated with death of patients with sepsis and critical illness: systematic review, meta-analysis …

R Taylor, C Zhang, D George, S Kotecha… - …, 2024 - thelancet.com
Background Mechanistic studies have established a biological role of sterol metabolism in
infection and immunity with clinical data linking deranged cholesterol metabolism during …

SARS‐CoV‐2 induced HDL dysfunction may affect the host's response to and recovery from COVID‐19

HM Al‐kuraishy, NR Hussien… - Immunity …, 2023 - Wiley Online Library
Introduction Covid‐19 is linked with the development of cardio‐metabolic disorders,
including dyslipidemia, dysregulation of high‐density lipoprotein (HDL), and low‐density …

Multifaced roles of HDL in sepsis and SARS-CoV-2 infection: Renal implications

A Stasi, R Franzin, M Fiorentino… - International journal of …, 2021 - mdpi.com
High-density lipoproteins (HDLs) are a class of blood particles, principally involved in
mediating reverse cholesterol transport from peripheral tissue to liver. Omics approaches …

The lipid biology of sepsis

K Amunugama, DP Pike, DA Ford - Journal of Lipid Research, 2021 - ASBMB
Sepsis, defined as the dysregulated immune response to an infection leading to organ
dysfunction, is one of the leading causes of mortality around the globe. Despite the …

Evaluation of the molecular mechanisms of sepsis using proteomics

H Miao, S Chen, R Ding - Frontiers in Immunology, 2021 - frontiersin.org
Sepsis is a complex syndrome promoted by pathogenic and host factors; it is characterized
by dysregulated host responses and multiple organ dysfunction, which can lead to death …