Light and circadian signaling pathway in pregnancy: Programming of adult health and disease

CN Hsu, YL Tain - International journal of molecular sciences, 2020 - mdpi.com
Light is a crucial environmental signal that affects elements of human health, including the
entrainment of circadian rhythms. A suboptimal environment during pregnancy can increase …

Epigenetic mechanisms involved in the effects of maternal hyperhomocysteinemia on the functional state of placenta and nervous system plasticity in the offspring

AV Arutjunyan, YP Milyutina, AD Shcherbitskaia… - Biochemistry …, 2023 - Springer
According to modern view, susceptibility to diseases, specifically to cognitive and
neuropsychiatric disorders, can form during embryonic development. Adverse factors …

[HTML][HTML] Role of melatonin in TLR4-mediated inflammatory pathway in the MTPT-induced mouse model

S Yildirim, A Ozkan, G Aytac, A Agar, G Tanriover - Neurotoxicology, 2022 - Elsevier
Neuroinflammation has an essential role in various neurodegenerative diseases including
Parkinson's disease (PD). Microglial activation as a result of neuroinflammation exacerbates …

Prenatal hyperhomocysteinemia induces glial activation and alters neuroinflammatory marker expression in infant rat hippocampus

AD Shcherbitskaia, DS Vasilev, YP Milyutina… - Cells, 2021 - mdpi.com
Maternal hyperhomocysteinemia is one of the common complications of pregnancy that
causes offspring cognitive deficits during postnatal development. In this study, we …

Maternal hyperhomocysteinemia induces neuroinflammation and neuronal death in the rat offspring cortex

AD Shcherbitskaia, DS Vasilev, YP Milyutina… - Neurotoxicity …, 2020 - Springer
Maternal hyperhomocysteinemia is one of the common complications of pregnancy that
causes offspring cognitive deficits during postnatal development. In the present work, we …

Methionine diet evoked hyperhomocysteinemia causes hippocampal alterations, metabolomics plasma changes and behavioral pattern in wild type rats

M Kovalska, E Baranovicova, D Kalenska… - International Journal of …, 2021 - mdpi.com
L-methionine, an essential amino acid, plays a critical role in cell physiology. High intake
and/or dysregulation in methionine (Met) metabolism results in accumulation of its …

Effects of aluminum oxide nanoparticles in the cerebrum, hippocampus, and cerebellum of male Wistar rats and potential ameliorative role of melatonin

NG Abdelhameed, YH Ahmed, NAE Yasin… - ACS Chemical …, 2023 - ACS Publications
Aluminum oxide nanoparticles (Al2O3 NPs) have been widely used in vaccine manufacture,
food additives, human care products, and cosmetics. However, they also have adverse …

Chemical hypermethioninemia in young mice: oxidative damage and reduction of antioxidant enzyme activity in brain, kidney, and liver

B de Moraes Meine, TS Franceschi, NP Bona… - Metabolic Brain …, 2023 - Springer
High levels of methionine (Met) and its metabolites, such as methionine sulfoxide (MetO),
found in hypermethioninemia, can be detrimental to the body; however, the underlying …

Effect of methionine diet on metabolic and histopathological changes of rat hippocampus

M Kovalska, P Hnilicova, D Kalenska… - International Journal of …, 2019 - mdpi.com
Hyperhomocysteinemia (hHcy) is regarded as an independent and strong risk factor for
cerebrovascular diseases, stroke, and dementias. The hippocampus has a crucial role in …

Effects of Aluminum Oxide Nanoparticles in the Spinal Cord of Male Wistar Rats and the Potential Ameliorative Role of Melatonin

NG Abdelhameed, YH Ahmed… - Environmental …, 2024 - Wiley Online Library
Aluminum oxide nanoparticles (Al2O3 NPs) are widely utilized in vaccine manufacturing and
other medical preparations. Melatonin has numerous effects as an antioxidant and anti …