Role of p38 MAPK signalling in testis development and male fertility
D Luo, Z He, C Yu, Q Guan - Oxidative medicine and cellular …, 2022 - Wiley Online Library
The testis is an important male reproductive organ, which ensures reproductive function via
the secretion of testosterone and the generation of spermatozoa. Testis development begins …
the secretion of testosterone and the generation of spermatozoa. Testis development begins …
Molecular markers: A new paradigm in the prediction of sperm freezability
M Ďuračka, F Benko, E Tvrdá - International Journal of Molecular …, 2023 - mdpi.com
For decades now, sperm cryopreservation has been a pillar of assisted reproduction in
animals as well as humans. Nevertheless, the success of cryopreservation varies across …
animals as well as humans. Nevertheless, the success of cryopreservation varies across …
Proteomic profiling of fallopian tube-derived extracellular vesicles using a microfluidic tissue-on-chip system
The human fallopian tube epithelium (hFTE) is the site of fertilization, early embryo
development, and the origin of most high-grade serous ovarian cancers (HGSOCs). Little is …
development, and the origin of most high-grade serous ovarian cancers (HGSOCs). Little is …
Hexachlorocyclohexane impairs human sperm motility by affecting lysine glutarylation and mitochondrial functions
L Yang, G Mei, Y Yang, J Cui, S Peng, Z Peng… - Food and Chemical …, 2023 - Elsevier
Decreased sperm motility is a leading cause of male infertility and persistent organic
pollutants are known to contribute significantly to the development of this disease. The …
pollutants are known to contribute significantly to the development of this disease. The …
Regulation of germline proteostasis by HSF1 and insulin/IGF-1 signaling
T Muhammad, J Li - Biochemical Society Transactions, 2023 - portlandpress.com
Protein homeostasis (proteostasis) is essential for cellular function and organismal health
and requires the concerted actions of protein synthesis, folding, transport, and turnover. In …
and requires the concerted actions of protein synthesis, folding, transport, and turnover. In …
KCNQ1 potassium channel expressed in human sperm is involved in sperm motility, acrosome reaction, protein tyrosine phosphorylation, and ion homeostasis during …
T Gao, K Li, F Liang, J Yu, A Liu, Y Ni, P Sun - Frontiers in physiology, 2021 - frontiersin.org
Potassium channels are involved in membrane hyperpolarization and ion homeostasis
regulation during human sperm capacitation. However, the types of potassium channels in …
regulation during human sperm capacitation. However, the types of potassium channels in …
Integrated metabolomics and phosphoproteomics reveal the protective role of exosomes from human umbilical cord mesenchymal stem cells in naturally aging mouse …
M Ling, C Tang, X Yang, N Yu, Y Song, W Ding… - Experimental Cell …, 2023 - Elsevier
Background Aging is characterized by a general decline in cellular function, which ultimately
affects whole body homeostasis. This study aimed to investigate the effects and underlying …
affects whole body homeostasis. This study aimed to investigate the effects and underlying …
Inhibition of p38MAPK signalling pathway alleviates radiation‐induced testicular damage through improving spermatogenesis
J Yang, X Ou, M Shu, J Wang, X Zhang… - British Journal of …, 2024 - Wiley Online Library
Abstract Background and Purpose Damage to the testis following exposure to ionizing
radiation has become an urgent problem to be solved. Here we have investigated if …
radiation has become an urgent problem to be solved. Here we have investigated if …
[HTML][HTML] Production of functional sperm from in vitro-cultured premeiotic spermatogonia in a marine fish
H Zhang, WW Zhang, CY Mo, MD Dong, KT Jia… - Zoological …, 2022 - ncbi.nlm.nih.gov
In vitro production of functional gametes can revolutionize reproduction by reducing
generation intervals and accelerating genetic breeding in aquaculture, especially in fish with …
generation intervals and accelerating genetic breeding in aquaculture, especially in fish with …
Analyzing the effect of heparin on in vitro capacitation and spermatozoal RNA population in goats
Heparin is a glycosaminoglycan polymer that is commonly used as an anticoagulant.
Heparin also induces in vitro capacitation in spermatozoa, although its molecular …
Heparin also induces in vitro capacitation in spermatozoa, although its molecular …