用于xla 基因疗法的优化的慢病毒载体

戴维德, 凯伦, 索默, 斯瓦蒂, 辛格 - 2020 - Google Patents
PGHMRUGBZOYCAA-UHFFFAOYSA-N 11, 19, 21-trihydroxy-22-[5-[5-(1-hydroxyethyl)-5-
methyloxolan-2-yl]-5-methyloxolan-2-yl]-4, 6, 8, 12, 14, 18, 20-heptamethyl-9-oxodocosa-10 …

Lentiviral vectors for therapeutic expression of btk in hematopoietic cells

L Elkouby, N DIAMANT, L Shachnai-Pinkas - 2022 - Google Patents
WO2022123559A1 - Lentiviral vectors for therapeutic expression of btk in hematopoietic cells -
Google Patents WO2022123559A1 - Lentiviral vectors for therapeutic expression of btk in …

Lentiviral vectors for therapeutic expression of BTK in haematopoietic cells

L Elkouby, N Diamant, L Shachnai-pinkas - US Patent 11,464,872, 2022 - Google Patents
The present application, in some embodiments, is directed to a polynucleotide including:(a)
a first nucleic acid molecule including a sequence of a human endogenous Bruton's tyrosine …

Optimized lentiviral vector for xla gene therapy

DJ Rawlings, K SOMMER, S SINGH - 2018 - Google Patents
BKZOUCVNTCLNFF-YQFKIGJWSA-N (2S)-2-[(2R, 3R, 4S, 5R, 6S)-2-hydroxy-6-[(1S)-1-[(2S,
7S, 8R, 9S)-2-[(2R, 5S)-5-[(2R, 3S, 4R, 5R)-5-[(2S, 3S, 4S, 5R, 6S)-6-hydroxy-4-methoxy-3 …