The mechanisms of action of prenylated xanthones against breast, colon, and lung cancers, and their potential application against drug resistance
Cancers such as breast, colon, and lung cancers are among the leading causes of death
with alarming increases in the number of new diagnoses and mortality rates. The non …
with alarming increases in the number of new diagnoses and mortality rates. The non …
[HTML][HTML] General toxicity studies of alpha mangostin from Garcinia mangostana: A systematic review
Alpha mangostin (AM), the main xanthone derivative contained in mangosteen pericarp
(Garcinia mangostana/GM), has many pharmacological activities such as antioxidant …
(Garcinia mangostana/GM), has many pharmacological activities such as antioxidant …
Metabolite Profiling of the Environmental-Controlled Growth of Marsilea crenata Presl. and Its In Vitro and In Silico Antineuroinflammatory Properties
B Ma'arif, FA Muslikh, D Amalia… - Borneo Journal of …, 2022 - journal.umpr.ac.id
This study was aimed to evaluate the metabolite contents and antineuroinflammatory
potential of Marsilea crenata Presl. grown under a controlled environmental condition. The …
potential of Marsilea crenata Presl. grown under a controlled environmental condition. The …
[HTML][HTML] 4-(4-Bromophenyl)-thiazol-2-amine derivatives: synthesis, biological activity and molecular docking study with ADME profile
D Sharma, S Kumar, B Narasimhan, K Ramasamy… - BMC chemistry, 2019 - Springer
In order to overcome the challenges of microbial resistance as well as to improve the
effectiveness and selectivity of chemotherapeutic agents against cancer, a novel series of 4 …
effectiveness and selectivity of chemotherapeutic agents against cancer, a novel series of 4 …
[HTML][HTML] In silico study of medicinal plants with cyclodextrin inclusion complex as the potential inhibitors against SARS-CoV-2 main protease (Mpro) and spike (S) …
D Dermawan, BA Prabowo, CA Rakhmadina - Informatics in medicine …, 2021 - Elsevier
The current outbreak of novel coronavirus disease (COVID-19) causes an alarming number
of deaths in 221 countries around the world. Nowadays, there is no specific and effective …
of deaths in 221 countries around the world. Nowadays, there is no specific and effective …
[HTML][HTML] New N-alkylated heterocyclic compounds as prospective NDM1 inhibitors: Investigation of in vitro and in silico properties
Y Kaddouri, B Bouchal, F Abrigach, M El Kodadi… - Pharmaceuticals, 2022 - mdpi.com
A new family of pyrazole-based compounds (1–15) was synthesized and characterized
using different physicochemical analyses, such as FTIR, UV-Visible, 1H, 13C NMR, and …
using different physicochemical analyses, such as FTIR, UV-Visible, 1H, 13C NMR, and …
Prediction of antiosteoporosis activity of thirty-nine phytoestrogen compounds in estrogen receptor-dependent manner through in silico approach
B Ma'arif, M Aminullah, NL Saidah… - … Journal of Natural …, 2021 - repository.uin-malang.ac.id
Osteoporosis is one of the health problems in postmenopausal women due to estrogen
deficiency. Phytoestrogen compounds can be used as an alternative osteoporosis treatment …
deficiency. Phytoestrogen compounds can be used as an alternative osteoporosis treatment …
[PDF][PDF] Anti-cancer and antimicrobial activity, in-silico ADME and docking studies of biphenyl pyrazoline derivatives
R Chinnamanyakar… - Biointerface Res. Appl …, 2021 - biointerfaceresearch.com
The present study deals with the multicomponent Michal addition reaction of xenyl chalcone
(10-17) reacting with hydrazine hydrate in the presence of ethane carboxylic acid. It afforded …
(10-17) reacting with hydrazine hydrate in the presence of ethane carboxylic acid. It afforded …
Synthesis, anticancer activity, structure–activity relationship, and molecular modeling studies of α-mangostin derivatives as hERα inhibitor
α-Mangostin is one of the secondary metabolites in mangosteen pericarp, which has been
reported to have anti-breast cancer activity. In our previous study, three α-mangostin …
reported to have anti-breast cancer activity. In our previous study, three α-mangostin …
In vitro anti-neuroinflammatory effect of genistein (4', 5, 7-trihydroxyisoflavone) on microglia HMC3 cell line, and in silico evaluation of its interaction with estrogen …
Objective: This study was aimed to evaluate the role of genistein or 4', 5, 7-
trihydroxyisoflavone as a phytoestrogen in the treatment of estrogen deficiency-induced …
trihydroxyisoflavone as a phytoestrogen in the treatment of estrogen deficiency-induced …