Irisin, a novel hormone like polypeptide, is cleaved and secreted by an unknown protease
from a membrane‐spanning protein, FNDC5 (fibronectin type III domain‐containing protein …

The pathophysiological mechanisms of diabetic cardiomyopathy have been extensively
studied, but there is still a lack of effective prevention and treatment methods. The ability of …

Myocardial infarction is the major cause of death in cardiovascular disease. In vitro and in
vivo models are used to find the exercise mode which has the most significant effect on …

The physiological functions of organs are intercommunicated occurring through secreted
molecules. That exercise can improve the physiological function of organs or tissues is …

Exercise has been recognized as an important non-pharmacological approach for the
prevention, treatment, and rehabilitation of cardiovascular diseases, but the mechanisms of …

Irisin, a product of the post-translational processing of fibronectin type III domain-containing
protein 5 (FNDC5), is a novel myokine which is upregulated during exercise. This hormone …

Irisin, a recently identified myokine, plays an important physiological role in modulating
energy homeostasis. However, the role of irisin in cardiac function during exercise has not …

Background: Regular exercise is an effective non-pharmacological therapy for treatment and
prevention of cardiovascular disease (CVD). The therapeutic benefits of exercise are …

Irisin, encoded by the FNDC5 (fibronectin type III domain containing 5) gene, is a novel
myokine that has been implicated as an essential mediator of exercise benefits. Effects of …

Ischemic stroke is a worldwide disease that seriously threatens human health, and there are
few effective drugs to treat it. Dihydromyricetin (DHM) has anti-inflammatory, antioxidant, and …