Role of the extremolytes ectoine and hydroxyectoine as stress protectants and nutrients: genetics, phylogenomics, biochemistry, and structural analysis
Fluctuations in environmental osmolarity are ubiquitous stress factors in many natural
habitats of microorganisms, as they inevitably trigger osmotically instigated fluxes of water …
habitats of microorganisms, as they inevitably trigger osmotically instigated fluxes of water …
[HTML][HTML] Stressed out: Bacterial response to high salinity using compatible solute biosynthesis and uptake systems, lessons from Vibrionaceae
GJ Gregory, EF Boyd - Computational and structural biotechnology journal, 2021 - Elsevier
Bacteria have evolved mechanisms that allow them to adapt to changes in osmolarity and
some species have adapted to live optimally in high salinity environments such as in the …
some species have adapted to live optimally in high salinity environments such as in the …
[HTML][HTML] Biosynthetic potential of the global ocean microbiome
Natural microbial communities are phylogenetically and metabolically diverse. In addition to
underexplored organismal groups, this diversity encompasses a rich discovery potential for …
underexplored organismal groups, this diversity encompasses a rich discovery potential for …
Biosynthesis of the stress-protectant and chemical chaperon ectoine: biochemistry of the transaminase EctB
AA Richter, CN Mais, L Czech, K Geyer… - Frontiers in …, 2019 - frontiersin.org
Bacteria frequently adapt to high osmolarity surroundings through the accumulation of
compatible solutes. Ectoine is a prominent member of these types of stress protectants and …
compatible solutes. Ectoine is a prominent member of these types of stress protectants and …
Osmotic adaptation and compatible solute biosynthesis of phototrophic bacteria as revealed from genome analyses
JF Imhoff, T Rahn, S Künzel, A Keller, SC Neulinger - Microorganisms, 2020 - mdpi.com
Osmotic adaptation and accumulation of compatible solutes is a key process for life at high
osmotic pressure and elevated salt concentrations. Most important solutes that can protect …
osmotic pressure and elevated salt concentrations. Most important solutes that can protect …
Biochemical diversity of 2-oxoglutarate-dependent oxygenases
RP Hausinger - 2015 - books.rsc.org
This chapter summarizes the diverse array of biochemical transformations that are catalysed
by Fe (ii)-and 2-oxoglutarate (2OG, also known as α-ketoglutarate)-dependent oxygenases …
by Fe (ii)-and 2-oxoglutarate (2OG, also known as α-ketoglutarate)-dependent oxygenases …
High-efficiency production of 5-hydroxyectoine using metabolically engineered Corynebacterium glutamicum
L Jungmann, SL Hoffmann, C Lang, R De Agazio… - Microbial Cell …, 2022 - Springer
Background Extremolytes enable microbes to withstand even the most extreme conditions in
nature. Due to their unique protective properties, the small organic molecules, more and …
nature. Due to their unique protective properties, the small organic molecules, more and …
The ups and downs of ectoine: structural enzymology of a major microbial stress protectant and versatile nutrient
Ectoine and its derivative 5-hydroxyectoine are compatible solutes and chemical
chaperones widely synthesized by Bacteria and some Archaea as cytoprotectants during …
chaperones widely synthesized by Bacteria and some Archaea as cytoprotectants during …
Composition and predicted metabolic capacity of upper and lower airway microbiota of healthy dogs in relation to the fecal microbiota
AC Ericsson, AR Personett, ME Grobman, H Rindt… - PloS one, 2016 - journals.plos.org
The upper and lower airways of healthy humans are reported to harbor stable and
consistent bacterial populations, and the composition of these communities is altered in …
consistent bacterial populations, and the composition of these communities is altered in …
Pangenomic comparison of globally distributed Poribacteria associated with sponge hosts and marine particles
Candidatus Poribacteria is a little-known bacterial phylum, previously characterized by
partial genomes from a single sponge host, but never isolated in culture. We have …
partial genomes from a single sponge host, but never isolated in culture. We have …