Since their invention in the early 2000s, tyrosine kinase inhibitors (TKIs) have gained
prominence as the most effective pathway-directed anti-cancer agents. TKIs have shown …

Taxanes (docetaxel and paclitaxel) are among the most commonly prescribed anticancer
drugs approved for the treatment of metastatic or locally advanced breast, non-small cell …

There has been a rapid emergence of numerous targeted agents in the oncology community
in the last decade. This exciting paradigm shift in drug development lends promise for the …

Patients treated with systemic anticancer drugs often show changes to their nails, which are
usually well tolerated and disappear on cessation of treatment. However, some nail toxicities …

Targeted drugs are increasingly being used for cancer management. They are designed to
block specific cancer cell processes, and are often better tolerated than conventional …

Microneedles have garnered significant interest as transdermal drug delivery route owing to
the advantages of nonselective loading capacity, minimal invasiveness, simple operation …

The epidermal growth factor receptor (EGFR) is highly expressed in a significant number of
human malignancies, and its expression is associated with tumor aggressiveness and …

Candida albicans is a fungal commensal and a major colonizer of the human skin, as well
as of the gastrointestinal and genitourinary tracts. It is also one of the leading causes of …

Imatinib mesylate is the first of a novel group of drugs that specifically target protein tyrosine
kinases, which are central to the pathogenesis of human cancer. It has been approved for …

Background Acute and subacute cutaneous side‐effects of epidermal growth factor receptor
inhibitors (EGFRIs) are very frequent and well known. Much less is known about the chronic …