Lipid-based nanocarriers for ocular drug delivery: An updated review

B Das, AK Nayak, S Mallick - Journal of Drug Delivery Science and …, 2022 - Elsevier
Recent years have witnessed a boom in ocular nanomedicine research with a number of
lipid-based nanocarriers such as liposomes, niosomes, cubosomes, nanoemulsions, solid …

A recent update on therapeutic potential of vesicular system against fungal keratitis

SN Sanap, A Kedar, AC Bisen, S Agrawal… - Journal of Drug Delivery …, 2022 - Elsevier
Fungal keratitis (FK) is a highly invasive and challenging corneal infection that can be
deadly if not treated well. Aspergillus, Fusarium, and Candida are the most common …

Tacrolimus loaded cationic liposomes for dry eye treatment

X Chen, J Wu, X Lin, X Wu, X Yu, B Wang… - Frontiers in …, 2022 - frontiersin.org
Eye drops are ophthalmic formulations routinely used to treat dry eye. However, the low
ocular bioavailability is an obvious drawback of eye drops owing to short ocular retention …

Formulation and evaluation of moxifloxacin loaded bilosomes in-situ gel: optimization to antibacterial evaluation

A Zafar, OA Alsaidan, SS Imam, M Yasir, KS Alharbi… - Gels, 2022 - mdpi.com
In this study, moxifloxacin (MX)-loaded bilosome (BS) in situ gel was prepared to improve
ocular residence time. MX-BSs were prepared using the thin-film hydration method. They …

Evaluation of conventional and hyaluronic acid-coated thymoquinone liposomes in an in vitro model of dry eye

E Landucci, C Mazzantini, M Calvani… - Pharmaceutics, 2023 - mdpi.com
Dry eye disease (DED) is a common ocular disorder characterized by an inadequate
lubrication of the eye by tears leading to inflammation and the alteration of the ocular …

Design and development of novel nutraceuticals: Current trends and methodologies

T Tsiaka, E Kritsi, K Tsiantas, P Christodoulou… - Nutraceuticals, 2022 - mdpi.com
Over the past few years, nutraceuticals have gained substantial attention due to the health-
promoting and disease-preventing functions behind their nutritional value. The global …

Bioactive molecules from plants: discovery and pharmaceutical applications

MC Bergonzi, CM Heard, J Garcia-Pardo - Pharmaceutics, 2022 - mdpi.com
The plant kingdom is one of the richest sources of bioactive compounds with pharmaceutical
potential. A special feature of higher plants is their ability to produce a great number of …

Formulation and evaluation of nano lipid carrier-based ocular gel system: optimization to antibacterial activity

SJ Gilani, MN Jumah, A Zafar, SS Imam, M Yasir… - Gels, 2022 - mdpi.com
The present research work was designed to prepare Azithromycin (AM)-loaded nano lipid
carriers (NLs) for ocular delivery. NLs were prepared by the emulsification–homogenization …

QbD-driven thymoquinone laden nanoemulsion for glaucoma management: In vitro, ex vivo, and pre-clinical evaluation

V Srivastava, ER Pardhi, R Yadav, V Singh… - Journal of Drug Delivery …, 2024 - Elsevier
The primary goal of the present research investigation is the development and evaluation of
thymoquinone-loaded nanoemulsion (TMQ-NE) for glaucoma therapy. The Box-Behnken …

Antinociceptive action of thymoquinone-loaded liposomes in an in vivo model of tendinopathy

L Micheli, L Di Cesare Mannelli, E Mosti, C Ghelardini… - Pharmaceutics, 2023 - mdpi.com
Tendinopathies represent about 45% of musculoskeletal lesions and they are a big burden
in clinics characterized by activity-related pain, focal tendon tenderness and intra-tendinous …