Successful treatment of cancer depends on early diagnosis and effective monitoring of
patients' response to therapy. Traditional tools based on tumor biopsies lack the sensitivity …

Introduction: MicroRNAs (miRNAs), which are evolutionarily conserved, and endogenous
non-coding RNAs, participate in the post-transcriptional regulation of eukaryotic genes. The …

To connect human biology to fish biomedical models, we sequenced the genome of spotted
gar (Lepisosteus oculatus), whose lineage diverged from teleosts before teleost genome …

MicroRNAs (miRNAs) broadly regulate gene expression through association with Argonaute
(Ago), which also protects miRNAs from degradation. However, miRNA stability is known to …

Research on non‐coding RNA (nc RNA) is a rapidly expanding field. Providing an official
gene symbol and name to nc RNA genes brings order to otherwise potential chaos as it …

Abstract Icefishes (suborder Notothenioidei; family Channichthyidae) are the only
vertebrates that lack functional haemoglobin genes and red blood cells. Here, we report a …

Clinical oncologists need more reliable and non-invasive diagnostic and prognostic
biomarkers to follow-up cancer patients. However, the existing biomarkers are often invasive …

The lack of an appropriate intracellular delivery system for therapeutic nucleic acids (TNAs)
is a major problem in molecular biology, biotechnology, and medicine. A relatively new class …

MicroRNAs (miRNAs) are widely present in many organisms and regulate the expression of
genes in various biological processes such as cell differentiation, metabolism, and …

Since miRNAs can participate in the posttranscriptional regulation of gene expression, they
may provide ideas for the development of new drugs or become new biomarkers for drug …