ISPAD clinical practice consensus guidelines 2022: Stages of type 1 diabetes in children and
adolescents Page 1 ISPAD GUIDELINES ISPAD clinical practice consensus guidelines 2022 …

Autoimmune polyendocrinopathies are traditionally divided into two distinct syndromes,
autoimmune polyendocrine syndrome type 1 and 2 (APS-1 and-2). The first is a monogenic …

This chapter serves as an update and replaces the 2018 ISPAD consensus guideline on
definition, epidemiology, and classification of diabetes in children and adolescents. 1 It …

• Diagnostic criteria for all types of diabetes in children and adolescents are based on
laboratory measurement of plasma blood glucose levels (BGL) and the presence or …

Type 1 diabetes mellitus (T1DM) results from the destruction of pancreatic β-cells that is
mediated by the immune system. Multiple genetic and environmental factors found in …

During the last decade, there have been substantial advances in the identification and
characterization of DNA sequence variants associated with individual predisposition to type …

OBJECTIVE Previously generated genetic risk scores (GRSs) for type 1 diabetes (T1D) have
not captured all known information at non-HLA loci or, particularly, at HLA risk loci. We …

Maria E Craiga, b, Craig Jefferiesc, Dana Dabelead, Naby Baldee, Anju Sethf and Kim C
Donaghuea aInstitute of Endocrinology and Diabetes, The Children's Hospital at Westmead …

Type 1 diabetes (T1D) results from immune‐mediated loss of pancreatic beta cells leading
to insulin deficiency. It is the most common form of diabetes in children, and its incidence is …

Type 1 diabetes (T1D) is a chronic autoimmune disease in which destruction or damaging of
the beta-cells in the islets of Langerhans results in insulin deficiency and hyperglycemia. We …