Because of the high catalytic activities and substrate specificity, natural enzymes have been
widely used in industrial, medical, and biological fields, etc. Although promising, they often …

Slowly but surely, Alzheimer's disease (AD) patients lose their memory and their cognitive
abilities, and even their personalities may change dramatically. These changes are due to …

Neurodegenerative diseases, a subset of age-driven diseases, have been known to exhibit
increased oxidative stress. The resultant increase in reactive oxygen species (ROS) has …

Dysregulation of glutathione homeostasis and alterations in glutathione-dependent enzyme
activities are increasingly implicated in the induction and progression of neurodegenerative …

Mitochondrial dysfunctions are supposed to be responsible for many neurodegenerative
diseases dominating in Alzheimer's disease (AD), Parkinson's disease (PD), and …

Bear bile has been used in Traditional Chinese Medicine for thousands of years due to its
therapeutic potential and clinical applications. The tauroursodeoxycholic acid (TUDCA), one …

Insulin signaling in central nervous system (CNS) has emerged as a novel field of research
since decreased brain insulin levels and/or signaling were associated to impaired learning …

Mitochondria play a vital role in the nervous system, as they are responsible for generating
energy in the form of ATP and regulating cellular processes such as calcium (Ca 2+) …

Alzheimer's disease, a neurodegenerative disease, is one of the most common causes of
dementia if elderly people worldwide. Alzheimer's disease leads to the alienation of …

Mitochondria play a vital role in maintaining cellular energy homeostasis, regulating
apoptosis, and controlling redox signaling. Dysfunction of mitochondria has been implicated …