Bias and class imbalance in oncologic data—towards inclusive and transferrable AI in large scale oncology data sets

E Tasci, Y Zhuge, K Camphausen, AV Krauze - Cancers, 2022 - mdpi.com
Simple Summary Large-scale medical data carries significant areas of underrepresentation
and bias at all levels: clinical, biological, and management. Resulting data sets and outcome …

The key differences between human papillomavirus-positive and-negative head and neck cancers: biological and clinical implications

SF Powell, L Vu, WC Spanos, D Pyeon - Cancers, 2021 - mdpi.com
Simple Summary Head and neck cancer (HNC) is the sixth most common cancer, causing
almost half a million deaths worldwide every year. The two subtypes of HNC are distinctly …

Current insights and progress in the clinical management of head and neck cancer

MN Amaral, P Faísca, HA Ferreira, MM Gaspar… - Cancers, 2022 - mdpi.com
Simple Summary Head and neck cancer (HNC) incidence has been steadily increasing
since the 1990s. While the multimodal treatment approach for localized HNC is well …

Phase II study of dichloroacetate, an inhibitor of pyruvate dehydrogenase, in combination with chemoradiotherapy for unresected, locally advanced head and neck …

SF Powell, M Mazurczak, EG Dib, JS Bleeker… - Investigational new …, 2022 - Springer
Chemoradiotherapy (CRT) for locally-advanced head and neck squamous cell carcinoma
(LA-HSNCC) yields 5-year survival rates near 50% despite causing significant toxicity …

An equity‐based narrative review of barriers to timely postoperative radiation therapy for patients with head and neck squamous cell carcinoma

EA Noyes, CA Burks, AR Larson… - Laryngoscope …, 2021 - Wiley Online Library
Objectives The majority of patients with head and neck squamous cell carcinoma (HNSCC)
do not commence postoperative radiation treatment (PORT) within the recommended 6 …

Neighborhood socioeconomic status and racial and ethnic survival disparities in oral cavity and laryngeal cancer

Y Liu, L Zhong, SV Puram, AL Mazul - Cancer Epidemiology, Biomarkers & …, 2023 - AACR
Background: Oral cavity cancer (OCC) and laryngeal cancer are among the most common
cancers worldwide. This study investigated survival in non-Hispanic (NH) Black, NH White …

Persistent ethnicity-associated disparity in antitumor effectiveness of immune checkpoint inhibitors despite equal access

MA Florez, JO Kemnade, N Chen, W Du… - Cancer research …, 2022 - AACR
We reviewed response to immune checkpoint inhibitors (ICI) of 207 patients with diagnoses
of lung or head and neck cancer treated with chemotherapy/ICI combination therapy and ICI …

Healthcare disparities in otolaryngology

S Batool, CA Burks, RW Bergmark - Current Otorhinolaryngology Reports, 2023 - Springer
Abstract Purpose of Review The purpose of this review is to summarize some of the recent
research studies on healthcare disparities across various subspecialties within …

The prognostic role of sex and hemoglobin levels in patients with oral tongue squamous cell carcinoma

M Tagliabue, O D'Ecclesiis, R De Berardinis… - Frontiers in …, 2022 - frontiersin.org
Background Women and men differ genetically, biologically (sex) and by social construct
(gender), possibly impacting on prognostic factors in predicting cancer survival. Hemoglobin …

Laryngeal Cancer and the End of Life (As We Know It)

MH Bodd, SD McCammon - Otolaryngologic Clinics of North …, 2023 - oto.theclinics.com
There are some things that are worse than death. To deny one's own integrity of personality
in the presence of the human challenge is one of those things. 1 Reverend Howard …