Abstract Type 1 diabetes (T1D) is an autoimmune disease characterized by loss of insulin
producing beta cells and reliance on exogenous insulin for survival. T1D is one of the most …

Despite extensive and ongoing investigations of the immune mechanisms of autoimmune
diabetes in humans and animal models, there is much less information about the natural …

OBJECTIVE To find a simple definition of partial remission in type 1 diabetes that reflects
both residual β-cell function and efficacy of insulin treatment. RESEARCH DESIGN AND …

Background: The honeymoon period (ie, partial remission) of type 1 diabetes mellitus is
characterized by reduced insulin requirements while good glycemic control is maintained …

Type 1 diabetes mellitus (T1DM) is characterized by irreversible islet β cell destruction.
During the progression of this disease, some patients with T1DM experience a phase of …

Type 1 diabetes, a chronic autoimmune disease, causes destruction of insulin-producing β-
cells over a period of years. Although many markers of the autoimmune process have been …

HB Mortensen, PGF Swift, RW Holl, P Hougaard, L Hansen, H Bjoerndalen, CE de Beaufort,
M Knip. Multinational study in children and adolescents with newly diagnosed type 1 …

There is a high incidence of metabolic syndrome among patients with primary aldosteronism
(PA), which has recently been associated with an unfavorable cardiometabolic profile …

OBJECTIVE To determine the prevalence of residual β-cell function (RBF) in children after 3–
6 years of type 1 diabetes, and to examine the association between RBF and incidence of …

Understanding active proinflammatory mechanisms at and before type 1 diabetes mellitus
(T1DM) onset is hindered in humans, given that the relevant tissues are inaccessible and …